Results 281 to 290 of about 1,049,911 (342)

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Adjunctive ketamine vs. buprenorphine in co-occurring major depressive disorder and opioid use disorder: a randomized, double-blind clinical trial assessing anxiety symptom severity and craving intensity. [PDF]

Trials
Mansoori A, Bazrafshan A, Ahmadi J, Mosavat SH.   +3 more
europepmc   +1 more source

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

Animal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong, Meiru Jiang, Kun Yuan, Fang Sheng, Xiuyun Xu, Yong Cui, Xijia Sun, Wenfei Tan   +7 more
wiley   +1 more source

Explanatory model of behavioral adaptation in video game addiction among adolescents in urban and rural Peru: the mediating role of anxiety. [PDF]

Front Psychol
Huamani-Cahua JC, Ojeda-Flores E, Medina Arce NR, Villanueva Kuong LE, Ojeda-Flores MA.   +4 more
europepmc   +1 more source

Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

Animal Models and Experimental Medicine, EarlyView.
The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley   +1 more source

Lacking ASIC1a in ASIC4-positive amygdala/bed nucleus of the stria terminalis (BNST) neurons reduces anxiety and innate fear in mice. [PDF]

J Biomed Sci
Chien YC, Lin SH, Lien CC, Wood JN, Chen CC.   +4 more
europepmc   +1 more source

Improved husbandry measures to enhance reproducibility of wound healing studies in the Leprdb/db mouse

Animal Models and Experimental Medicine, EarlyView.
Though the Leprdb/db mouse is a common and well‐studied model of type II diabetes mellitus, there are a few specific guidelines for its husbandry, and wound complications are common. We present a modified husbandry approach for the Leprdb/db mouse that includes increased cage size, decreased housing density, and more frequent cage changes.
May Barakat, Brian P. David, Junhe Shi, Angela Xu, Terry W. Moore, Lin Chen, Luisa A. DiPietro   +6 more
wiley   +1 more source

A cross-sectional study on resilience and death anxiety among emergency nurses. [PDF]

BMC Nurs
El-Ashry AM, Abdallah HMM, Elsayed SM, Khedr MA, El-Sayed MM, Ghoneam MA.   +5 more
europepmc   +1 more source

Studying the influence of single social interactions on approach and avoidance behavior: A multimodal investigation in immersive virtual reality. [PDF]

Behav Res Methods
Gado S, Gamer M.
europepmc   +1 more source

Effectiveness of immersive VR therapy in reducing stress-associated symptoms in Ukraine. [PDF]

Eur J Psychotraumatol
Kukharuk O, Tkalich K, Kamash N, Georgiou O.   +3 more
europepmc   +1 more source