Results 31 to 40 of about 2,964,538 (363)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Neural and behavioral markers of inhibitory control predict symptom improvement during internet-delivered cognitive behavioral therapy for depression

open access: yesTranslational Psychiatry
Poor inhibitory control contributes to deficits in emotion regulation, which are often targeted by treatments for major depressive disorder (MDD), including cognitive behavioral therapy (CBT).
Michelle Thai   +9 more
doaj   +1 more source

Plasticity and Anxiety [PDF]

open access: yesNeural Plasticity, 2007
Anxiety is a very broad behavioural trait, helping animals to cope with dangerous environmental situations. As anxiety is linked to other emotional processes and to cognitive functions such as learning and memory, it involves a number of cerebral structures and brain transmitter systems, thereby giving rise to a high degree of plasticity.
Georges Chapouthier, Patrice Venault
openaire   +3 more sources

Dealing with anxiety:Relationships among interpersonal attachment style, psychological wellbeing and trait anxiety [PDF]

open access: yes, 2017
Anxiety is a major contributor to poor quality mental health for many people in our community, and is a leading cause of presentations at medical and health clinics.
Andrews, Emma, Hicks, Richard E.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Traumatic stress alters neural reactivity to visual stimulation

open access: yesNPP-Digital Psychiatry and Neuroscience
Traumatic stress is a precursor to the development of posttraumatic stress disorder (PTSD). Emergent research suggests visual processing regions may be relevant to PTSD development; however, no previous research to date has investigated the potential ...
Nathaniel G. Harnett   +6 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Prospective cognitions in anxiety and depression: Replication and methodological extension [PDF]

open access: yes, 2000
The present study presents a replication and methodological extension of MacLeod, Tata, Kentish, and Jacobsen (1997) with a nonclinical sample, using future-directed imagery to assess prospective cognitions.
Alloy L. B.   +5 more
core   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

open access: yesFEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Does Repeated Ticking Maintain Tic Behavior? An Experimental Study of Eye Blinking in Healthy Individuals

open access: yesBehavioural Neurology, 2014
Tics in Tourette syndrome (TS) are often preceded by “premonitory urges”: annoying feelings or bodily sensations. We hypothesized that, by reducing annoyance of premonitory urges, tic behaviour may be reinforced.
Daniel J. V. Beetsma   +4 more
doaj   +1 more source

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