Results 81 to 90 of about 1,225,873 (314)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Explainable counterfactual reasoning in depression medication selection at multi-levels (personalized and population)

BMC Medical Informatics and Decision Making
Background This study investigates how variations in Major Depressive Disorder (MDD) symptoms (HAM-D) are associated in a predictive model with randomized clinical trial (RCT) arm assignment between SSRIs and SNRIs.
Xinyu Qin, Mark H. Chignell, Alexandria Greifenberger, Sachinthya Lokuge, Elssa Toumeh, Tia Sternat, Martin Katzman, Lu Wang   +7 more
doaj   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Augmenting the efficacy of benzodiazepine taper with telehealth-delivered cognitive behavioral therapy for anxiety disorders in patients using prescription opioids: A pilot randomized controlled trial [PDF]

, 2023
Kate Wolitzky‐Taylor, Larissa J. Mooney, Michael W. Otto, Allison Metts, E. Marie Parsons, Maria Hanano, Reuben J Ram   +6 more
openalex   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

International Journal of Depression and Anxiety [PDF]

, 2019
Jeff Cain, Jordan Kelley, Daniel R. Malcom, C Tossell, P Kortum, C Shepard, A Rahmati, L Zhong, J Cain, M Peters, C Godfrey, H Khalil, P Mcinerney, D Parker, H Arksey, O' Malley, L, D Moher, L Shamseer, M Clarke, Davina, Alessandro, M Ouzzani, H Hammady, Z Fedorowicz, A Elmagarmid, F Alosaimi, H Alyahya, H Alshahwan, Al Mahyijari, N Shaik, S, J Boumosleh, D Jaalouk, N Cheever, L Rosen, L Carrier, A Chavez, L Chen, Z Yan, W Tang, F Yang, X Xie, B Chen, F Liu, S Ding, X Ying, L Wang, S Choi, D Kim, J Choi, A Heejune, Eun Jeung, C, A Deepali, M Shobha, P Reddy, K Demirci, M Akgonul, A Akpinar, J Elhai, M Tiamiyu, J Weeks, J Levine, K Picard, M Eyvazlou, E Zarei, A Rahimi, M Abazari, R Katz-Sidlow, A Ludwig, S Miller, R Sidlow, D Derks, A Bakker, S Klauer, F Guo, B Simons-Morton, M Ouimet, S Lee, M Sapacz, G Rockman, J Clark, S Tao, X Wu, Y Zhang, S Zhang, S Tong, S Tao, X Wu, S Zhang, S Tong, J Hao, J Wang, H Wang, J Gaskin, L Wang, Y Lin, L Chang, Y Lee   +99 more
openalex   +1 more source

eLife assessment: Approach-avoidance reinforcement learning as a translational and computational model of anxiety-related avoidance

, 2023
Claire M. Gillan
openalex   +1 more source

Preparatory Study of Anxiety towards Sleep Quality and Physical Fitness of Elite Badminton Players [PDF]

, 2023
Mohamad Ikram Mat Saad, Wan Ahmad Munsif Wan Pa   +1 more
openalex   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Adverse childhood events and clinical manifestation of anxiety symptoms in Greek adolescents during COVID-19 pandemic

, 2023
Aikaterini Marini, Ignatia Farmakopoulou, Evgenia Gkintoni, Maria Theodoratou, Gerasimos Kolaitis   +4 more
openalex   +1 more source