Results 11 to 20 of about 977,682 (313)

Neuroimaging in anxiety disorders [PDF]

Journal of Neural Transmission, 2008
Neuroimaging studies have gained increasing importance in validating neurobiological network hypotheses for anxiety disorders. Functional imaging procedures and radioligand binding studies in healthy subjects and in patients with anxiety disorders provide growing evidence of the existence of a complex anxiety network, including limbic, brainstem ...
Engel, Kirsten, Bandelow, Borwin, Gruber, Oliver, Wedekind, Dirk   +3 more
openaire   +4 more sources

The unified protocol for transdiagnostic treatment of emotional disorders compared with diagnosis-specific protocols for anxiety disorders a randomized clinical trial [PDF]

, 2017
IMPORTANCE: Transdiagnostic interventions have been developed to address barriers to the dissemination of evidence-based psychological treatments, but only a few preliminary studies have compared these approaches with existing evidence-based ...
Ametaj, Amantia, Barlow, David H., Bentley, Kate H., Boettcher, Hannah T., Boswell, James F., Bullis, Jacqueline R., Carl, Jenna R., Cassiello-Robbins, Clair, Conklin, Laren R., Farchione, Todd J., Gallagher, Matthew W., Murray-Latin, Heather, Sauer-Zavala, Shannon, Thompson-Hollands, Johanna   +13 more
core   +1 more source

Transdiagnostic treatment of bipolar disorder and comorbid anxiety using the Unified Protocol for Emotional Disorders: A pilot feasibility and acceptability trial [PDF]

, 2017
BACKGROUND Comorbid anxiety in bipolar disorder (BD) is associated with greater illness severity, reduced treatment response, and greater impairment. Treating anxiety in the context of BD is crucial for improving illness course and outcomes. The current
Baek, Ji Hyun, Barlow, David H., Bernstein, Emily E., Deckersbach, Thilo, Ellard, Kristen K., Hearing, Casey, Nierenberg, Andrew A., Sylvia, Louisa G.   +7 more
core   +1 more source

Emotion regulation difficulties related to depression and anxiety : a network approach to model relations among symptoms, positive reappraisal, and repetitive negative thinking [PDF]

, 2019
Frequent repetitive negative thinking and infrequent positive reappraisal use are theorized to increase risk for depression and anxiety. Yet, research has studied these regulatory strategies at the disorder level, ignoring the clinical heterogeneity and ...
Everaert, Jonas, Joormann, Jutta
core   +2 more sources

The effect of heart rate variability biofeedback training on stress and anxiety: a meta-analysis [PDF]

, 2017
BACKGROUND: Some evidence suggests that heart rate variability (HRV) biofeedback might be an effective way to treat anxiety and stress symptoms. To examine the effect of HRV biofeedback on symptoms of anxiety and stress, we conducted a meta-analysis of ...
Curtiss, Joshua E., Goessl, Vera C., Hofmann, Stefan G.   +2 more
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Protocol for a randomized controlled trial examining multilevel prediction of response to behavioral activation and exposure-based therapy for generalized anxiety disorder. [PDF]

, 2020
BACKGROUND:Only 40-60% of patients with generalized anxiety disorder experience long-lasting improvement with gold standard psychosocial interventions. Identifying neurobehavioral factors that predict treatment success might provide specific targets for ...
Abelson, J, Akeman, E, Aupperle, Robin L, Bodurka, J, Clausen, AN, Cosgrove, KT, Craske, MG, Kirlic, N, Martell, C, Mathis, B, McDermott, TJ, Paulus, M, Santiago, J, Thompson, WK, Wolitzky-Taylor, K   +14 more
core   +1 more source

Mindfulness-based cognitive therapy v. group psychoeducation for people with generalised anxiety disorder: randomised controlled trial [PDF]

, 2016
Background: Research suggests that an 8-week mindfulness-based cognitive therapy (MBCT) course may be effective for generalised anxiety disorder (GAD).
Chan, Peter Hoi Sing, Cheung, Eliza Yee Lai, Gao, Ting, Griffiths, Sian M., Lee, Tatia Mei Chun, Ling, Candy Yuet Man, Lo, Herman Hay Ming, Lui, Wacy Wai Sze, Ma, Helen Shuk Wah, Mak, Winnie Wing Sze, Mercer, Stewart, Tang, Wai Kwong, Wong, Samuel Yeung Shan, Wu, Justin Che Yuen, Yip, Benjamin Hon Kei   +14 more
core   +1 more source

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo, Kilian Hett, Amy Cooper, Amy E. Brown, Jessica Iregui, Manus J. Donahue, M. Erik Landman, Italo Biaggioni, Margaret Bradbury, Cynthia Wong, David Stamler, Daniel O. Claassen   +11 more
wiley   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source