Results 51 to 60 of about 411,877 (311)

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Social Anxiety Disorder and Alcohol Use Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2010
High rates of comorbidity were found between alcohol use disorders and social anxiety disorder in epidemiologic studies. Although many studies show strong relationship between social anxiety disorder and alcohol use disorder diagnosis, inconsistency ...
Cuneyt Evren
doaj  

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Validity of the five‐item mental health inventory for screening current mood and anxiety disorders in the general population

International Journal of Methods in Psychiatric Research
Objectives The Mental Health Inventory (MHI‐5) is frequently used as a screener for mood and anxiety disorders. However, few population‐based studies have validated it against a diagnostic instrument assessing disorders following current diagnostic ...
Margreet Ten Have, Marja J. H. Van Bon‐Martens, Frederiek Schouten, Saskia Van Dorsselaer, Laura Shields‐Zeeman, Annemarie I. Luik   +5 more
doaj   +1 more source

Prevalence of illness anxiety disorder among recovered patients after hospitalization with COVID-19 [PDF]

فصلنامه ابن سینا, 2023
Background and aims: Covid-19 has the potential to trigger heightened health anxiety and concerns about health repercussions. This study aimed to investigate the prevalence of illness anxiety disorder among individuals who have recovered from Covid-19 ...
Hafez Safari, Seyedabdolmajid Bahrainian, Mohammad Hassan Ghanifar   +2 more
doaj  

Anxiety Disorders in Dogs [PDF]

, 2011
Dogs have been one of the closest domesticated animals to men who live with them, and in the majority of cases bond in such a way that they represent another family member, reason why their behaviour affects the common welfare directly. Changes in dogs’ behaviour represent a serious problem that threatens not only the physical integrity and general ...
Miguel Ibáñez Talegón, Bernadette Anzola Delgado   +1 more
openaire   +4 more sources

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Prevalence and comorbidity of anxiety disorder in school-attending children and adolescents aged 6–16 years in China

BMJ Paediatrics Open
Background The reported prevalence rate of anxiety disorder in the paediatric population varies widely between different counties. Currently, there is no national epidemiological survey of childhood anxiety disorder in China.
Rui Wang, Hui Xu, Ying Li, Fang Wang, Yi Zheng, Hanxue Yang, Fenghua Li, Yonghua Cui   +7 more
doaj   +1 more source