Results 51 to 60 of about 977,682 (313)
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou+16 more
wiley +1 more source
COMORBID ANXIETY IN PATIENTS WITH PSYCHOSIS [PDF]
A diagnosis of psychosis has tended to discount the considerable degree of emotional disorder associated with it, in a manner that may also inform psychological treatment options. Depression and anxiety are often associated with schizophrenia.
Lilijana Šprah+1 more
core +1 more source
Pharmacology and prescribing in anxiety [PDF]
In this article in the series of ‘bite sized’ pharmacology, we will look at the pharmacological actions of drugs used in the management of anxiety disorders.
Robertson, DAF
core +2 more sources
Anxiety Disorders in Dogs [PDF]
Dogs have been one of the closest domesticated animals to men who live with them, and in the majority of cases bond in such a way that they represent another family member, reason why their behaviour affects the common welfare directly. Changes in dogs’ behaviour represent a serious problem that threatens not only the physical integrity and general ...
Miguel Ibáñez Talegón+1 more
openaire +4 more sources
Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu+15 more
wiley +1 more source
Anger: the unrecognized emotion in emotional disorders [PDF]
Anger plays a prominent definitional role in some psychological disorders currently widely scattered across DSM‐5 categories (e.g., intermittent explosive disorder, borderline personality disorder).
Barlow, David H.+1 more
core +1 more source
Memory and anxiety disorders [PDF]
Experimental psychopathologists have identified varying patterns in memory bias in people with depressive and anxiety disorders. Individuals suffering from depression tend to exhibit explicit memory deficits for positively-valanced material, and sometimes exhibit biases for retrieving negative self-relevant information as well.
openaire +4 more sources
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang+10 more
wiley +1 more source
Acceptability and proof of concept of internet-delivered treatment for depression, anxiety, and stress in university students: protocol for an open feasibility trial [PDF]
BACKGROUND: In recent years, university counseling and mental health services have reported an increase in the number of clients seeking services and in yearly visits.
Beidel, Deborah+6 more
core +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source