Results 171 to 180 of about 23,910 (287)

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiety while improving patient acceptance and procedural quality. In Japan, benzodiazepines such as midazolam and opioid analgesics have long been widely used in routine clinical practice; however, many of these agents historically
Ryoji Ichijima   +13 more
wiley   +1 more source

Efficacy of Mindfulness and Cognitive Behavioral Therapies for Depression and Anxiety in Individuals With Cancer: A Meta‐Analysis

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
A meta‐analysis of 96 randomized controlled trials (RCTs) involving 14 937 adults with cancer shows that both cognitive behavioral therapy (CBT) and mindfulness‐based interventions (MBIs) reduce anxiety and depression. CBT demonstrates larger overall effects, whereas MBIs provide sustained benefits and perform well in digital formats, supporting ...
Kenni Wojujutari Ajele   +1 more
wiley   +1 more source

Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities. [PDF]

open access: yesJ Intellect Disabil Res
ABSTRACT Background Psychotropic use and psychotropic polypharmacy are common in people with intellectual disabilities, but representative population‐based studies on this topic are scarce. We evaluated the prevalence of psychotropic use and psychotropic polypharmacy in a Finnish nationwide cohort of people with intellectual disabilities aged 0–97 ...
Virtanen V   +6 more
europepmc   +2 more sources

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia   +10 more
wiley   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis   +1 more
wiley   +1 more source

Depression and Anxiety Among Patients with COPD: A Nationwide Study from Lithuania. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Valiulis T   +3 more
europepmc   +1 more source

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