Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study. [PDF]
Bartholomä WC +7 more
europepmc +1 more source
A Deep Learning Framework for Forecasting Medium‐Term Covariance in Multiasset Portfolios
ABSTRACT Forecasting the covariance matrix of asset returns is central to portfolio construction, risk management, and asset pricing. However, most existing models struggle at medium‐term horizons, several weeks to months, where shifting market regimes and slower dynamics prevail.
Pedro Reis, Ana Paula Serra, João Gama
wiley +1 more source
Management of acute otitis media with otorrhea in Italian pediatric practice: a national survey. [PDF]
Marchisio P +5 more
europepmc +1 more source
Study of prognostic factors in AOM
Ogami, Masashi +6 more
openaire +1 more source
Prevalence of Pre‐Clinical Obesity Among US Adults Receiving Medical and Surgical Obesity Treatment
ABSTRACT Objective We sought to determine how the proportion of adults historically receiving obesity interventions would be classified under the recently proposed “pre‐clinical” and “clinical” obesity classifications and the impact of this change on safety and outcomes.
Jason M. Samuels +4 more
wiley +1 more source
Epoxy Clerodane Diterpene (ECD) significantly reduces adipocyte hypertrophy and lipid accumulation in human mesenchymal stem cell (hMSC)‐derived adipocytes. ECD improves mitochondrial membrane potential (ΔΨm), increases thermogenic regulators (UCP‐1, PPARγC1α), decreases adipogenic markers (C/EBPα, PPARγ), and reduces inflammatory mediators (TNF‐α, NF ...
Sahar Abdulaziz AlSedairy +4 more
wiley +1 more source
ABSTRACT Background Acute kidney injury (AKI) is a common and serious complication after cardiac arrest, affecting more than 30% of initially successfully resuscitated patients, with around 10% receiving Kidney Replacement Therapy (KRT). Currently, treatment options to prevent renal complications are limited.
Keski‐Keturi M +76 more
wiley +1 more source
Prevalence and Global Distribution of Bacterial Species Associated with Acute Otitis Media in Children: Systematic Review and Meta-Analysis. [PDF]
Kim HO +9 more
europepmc +1 more source
Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes
Urinary ECV miRNAs show a distinct dysregulation signature in T2D with strong diagnostic performance. This signature mirrors molecular changes across pancreatic islets, blood, liver, and adipose tissue, with the strongest concordance in islets, linking it to β‐cell stress. Overall, they represent a non‐invasive, mechanistically informative biomarker of
Md. Zubbair Malik +10 more
wiley +1 more source
Garlic Polysaccharides Ameliorate AOM/DSS-Induced Colon Tumorigenesis: A Multi-Omics Mechanistic Study. [PDF]
Qi Y, Lu X, Li L, Zheng Z, Qiao Y.
europepmc +1 more source

