Results 21 to 30 of about 20,895 (217)

Effect of Angiogenesis and Lymphangiogenesis in Diesel Exhaust Particles Inhalation in Mouse Model of LPS Induced Acute Otitis Media

Frontiers in Cellular and Infection Microbiology, 2022
Lymphangiogenesis and angiogenesis might have significant involvement in the pathogenesis of otitis media with effusion. This study investigated the effect of diesel exhaust particles (DEP) on inflammation and lymphangiogenesis in a mouse model of acute ...
Byeong-Gon Kim, Byeong-Gon Kim, Da Yeon Choi, Min-Gyoung Kim, An-Soo Jang, Myung-Whan Suh, Myung-Whan Suh, Jun Ho Lee, Jun Ho Lee, Seung Ha Oh, Seung Ha Oh, Moo Kyun Park, Moo Kyun Park   +12 more
doaj   +1 more source

Ecological and dynamic analysis of gut microbiota in the early stage of azomethane-dextran sodium sulfate model in mice

Frontiers in Cellular and Infection Microbiology, 2023
The success rate of azomethane-dextran sodium sulfate (AOM-DSS) model in mice has been a long-standing problem. Treatment of AOM and the first round DSS induces acute colitis and is of great significance for the success of AOM-DSS model.
Ruizheng Sun, Ruizheng Sun, Ruizheng Sun, Ruizheng Sun, Hao Chen, Siqi Yao, Zheng Yu, Chen Lai, Chen Lai, Chen Lai, Jing Huang   +10 more
doaj   +1 more source

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

Advanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner, Dhananjeya Kumaar, Giacomo Torti, Killian Keller, Till Zellweger, Florian M. Schenk, Christoph Weilenmann, Daniel Chelladurai, Vara Prasad Jonnalagadda, Ghazi Sarwat Syed, Vanessa Wood, Jürg Leuthold, Alexandros Emboras, Maksym Yarema, Mathieu Luisier   +14 more
wiley   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

AOM in children.

BMJ clinical evidence, 2011
INTRODUCTION: In the UK, about 30% of children under 3 years of age visit their GP each year with acute otitis media (AOM), and 97% of these receive antibiotics. In the US, AOM is the most common reason for outpatient antibiotic treatment. Without antibiotics, AOM resolves within 24 hours in about 60% of children, and within 3 days in about 80% of ...
Damoiseaux, R.A., Rovers, M.M., Rovers, M.M.   +2 more
openaire   +4 more sources

NKR-P1A/CD161: A Multifunctional Immune Receptor at the Crossroads of Antitumor Immunity

Biomolecules
The immune response of our body, whether it is directed to infective agents, allergens, or tumors, should support our recovery but can also be dangerous if dysregulated.
Chiara Rosa Maria Uras, Martina Taglieri, Linda Di Gregorio, Alessandro Poggi   +3 more
doaj   +1 more source

Efficacy of 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine against acute otitis media and nasopharyngeal carriage in Panamanian children – A randomized controlled trial

Human Vaccines & Immunotherapeutics, 2017
We previously reported 10-valent pneumococcal non-typeable Haemophilus influenzae (NTHi) protein D conjugate vaccine (PHiD-CV) efficacy in a double-blind randomized trial (ClinicalTrials.gov: NCT00466947) against various diseases, including acute otitis ...
Xavier Sáez-Llorens, Stella Rowley, Digna Wong, Mirna Rodríguez, Arlene Calvo, Marisol Troitiño, Albino Salas, Vielka Vega, Maria Mercedes Castrejón, Patricia Lommel, Thierry G. Pascal, William P. Hausdorff, Dorota Borys, Javier Ruiz-Guiñazú, Eduardo Ortega-Barría, Juan Pablo Yarzabal, Lode Schuerman   +16 more
doaj   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database

BMC Pediatrics, 2012
Background The incidence of acute otitis media (AOM) vary from country to country. Geographical variations together with differences in study designs, reporting and settings play a role.
Marchisio Paola, Cantarutti Luigi, Sturkenboom Miriam, Girotto Silvia, Picelli Gino, Dona Daniele, Scamarcia Antonio, Villa Marco, Giaquinto Carlo   +8 more
doaj   +1 more source

mRNA-based seasonal influenza vaccines: an overview of immunogenicity, efficacy, and safety

Frontiers in Immunology
Available seasonal influenza vaccines, most of which are still produced in eggs, have several limitations. Messenger RNA (mRNA) technology has emerged as a transformative approach capable of overcoming some of these shortcomings.
Alexander Domnich, Andrea Orsi, Andrea Orsi, Andrea Orsi   +3 more
doaj   +1 more source