Results 191 to 200 of about 85,179 (239)

Staging metastatic urothelial cancer with Nectin‐4 imaging using Gallium‐68‐N188 PET/CT

open access: yesBJU International, Volume 137, Issue 1, Page 166-172, January 2026.
Objective To quantify Nectin‐4 expression in tumour lesions using the Nectin‐4‐binding peptide Gallium‐68‐N188 and positron emission tomography (PET)/computed tomography (CT) in patients with advanced or metastasised urothelial cancer eligible for therapy with the Nectin‐4‐directed antibody–drug conjugate enfortumab vedotin, in combination with ...
Matthias Miederer   +10 more
wiley   +1 more source

Increased ATP production and P‐glycoprotein activity underlie the marked changes in blood–brain barrier transport of drugs in a mouse model of amyotrophic lateral sclerosis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 280-295, January 2026.
Background and purpose Patients with amyotrophic lateral sclerosis (ALS) are prescribed many medications for symptomatic relief. However, how potential alterations to the blood–brain barrier (BBB) affect the brain exposure of drugs in ALS remains under‐investigated. Experimental approach We used high‐dimensional proteomic analysis, cellular metabolism,
Yijun Pan   +10 more
wiley   +1 more source

Neoadjuvant Under‐Dilated TIPS: Expanding Surgeries for Extrahepatic Malignancies in Patients With Cirrhosis and CSPH

open access: yesLiver International, Volume 46, Issue 1, January 2026.
ABSTRACT Background & Aims Portal hypertension is a major challenge in patients with cirrhosis requiring surgery. This study aimed to evaluate the efficacy of under‐dilated neoadjuvant transjugular intrahepatic portosystemic shunt (U.N‐TIPS) in enabling elective extrahepatic oncologic surgery in patients with cirrhosis and clinically significant portal
Dario Saltini   +22 more
wiley   +1 more source

Thoracic endovascular aortic repair for traumatic and non-traumatic rupture of the descending thoracic aorta: A 15-year single-centre experience. [PDF]

open access: yesInt J Cardiol Heart Vasc
Berkenheide R   +10 more
europepmc   +1 more source

Aortoesophageal fistula: Long-term survival with aggressive multidisciplinary management. [PDF]

open access: yesJTCVS Tech
Calderon-Rojas R   +13 more
europepmc   +1 more source

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