Results 81 to 90 of about 85,179 (239)

Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu   +5 more
wiley   +1 more source

Surgical Management of Substernal Goiters: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 15,706 patients with substernal goiter highlights that while surgery is often prompted by symptoms or imaging evidence of compression, over a quarter of patients were asymptomatic. The majority of cases (88.7%) were successfully managed through a cervical approach, with only a minority requiring thoracic ...
Matthew H. Cheung   +4 more
wiley   +1 more source

The Epidemiology of Aortic Aneurysms: Global and Regional Trends Between 1990 and 2021

open access: yesMedicine Advances, EarlyView.
This study presents the first comprehensive global analysis of the burden and inequality of aortic aneurysm (AA) using GBD 2021 data across 204 countries and territories. While the overall global burden of AA has declined over the past three decades, our findings reveal a concerning rise in AA‐related mortality and disability‐adjusted life years (DALYs)
Jiarui Zhang   +7 more
wiley   +1 more source

Feasibility Study for Dual Phase Free Breathing 3D bSSFP MRA With Preserved Eddy‐Current Tolerance With Adaptive k‐Space Lengths (PETAL) Acquisition

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate the feasibility of a novel dual‐phase self‐navigated, free‐breathing balanced steady‐state free‐precession whole‐heart MRA acquisition for aortic annulus size measurement using a Cartesian trajectory that mitigates eddy‐current artifacts by minimizing k‐space jumps between consecutive readouts with predictable scan times.
Tassia Ribeiro Salles Moura   +11 more
wiley   +1 more source

A morphological indicator for aortic dissection: fitting circle of the thoracic aorta

open access: yesBMC Cardiovascular Disorders
Background This study aims to identify a morphological indicator of aortic dissection (AD) based on the geometrical characteristics of the thoracic aorta.
Hongji Pu   +12 more
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa   +7 more
wiley   +1 more source

Diagnostic Yield of Post‐Mortem Fetal Micro‐CT for Thoracic Abnormalities

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective This study aims to identify the imaging findings specifically for thoracic anomalies in 1200 Micro‐CT cases, independent of whether the abnormality contributed to the main diagnosis or cause of death. Method We analyzed 1200 Micro‐CT scans in an unselected, consecutive cohort between 2017 and 2024 to identify thoracic anomalies ...
Ian C. Simcock   +5 more
wiley   +1 more source

Assessment of Double Outlet Left Ventricle in Pediatrics Using Transthoracic Echocardiography and Computed Tomographic Angiography

open access: yesPediatric Discovery, EarlyView.
The clinical manifestation of DOLV was atypical. TTE has a relatively high diagnostic accuracy for DOLV in pediatric, which is very valuable for its early detection. ABSTRACT Double outlet left ventricle (DOLV) is a rare congenital cardiac anomaly in which both great arteries originate entirely or predominantly from the morphologic left ventricle.
Xu Zhu   +6 more
wiley   +1 more source

Distal Extent of Resection in Type A Dissection: Keeping It Simple [PDF]

open access: yesTexas Heart Institute Journal
Marc R. Moon, MD, Puja Kachroo, MD
doaj   +1 more source

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