Results 121 to 130 of about 232,794 (224)

Deep Supervision by Gaussian Pseudo-label-based Morphological Attention for Abdominal Aorta Segmentation in Non-Contrast CTs [PDF]

arXiv
The segmentation of the abdominal aorta in non-contrast CT images is a non-trivial task for computer-assisted endovascular navigation, particularly in scenarios where contrast agents are unsuitable. While state-of-the-art deep learning segmentation models have been proposed recently for this task, they are trained on manually annotated strong labels ...
arxiv  

Outermost Cationic Surface Charge of Layer‐by‐Layer Films Prevents Endothelial Cells Migration for Cell Compartmentalization in Three‐Dimensional Tissues

Advanced Science, EarlyView.
A nanometer‐sized artificial basement membrane (A‐BM) is developed to replicate the barrier functions of the basement membrane and prevent cell migration. It is demonstrated that the outermost cationic surface charge of nanofilms can effectively inhibit endothelial cell migration and sprouting, allowing for the construction of 3D patterned vascular ...
Jinfeng Zeng, Sven Heilig, Matthias Ryma, Jürgen Groll, Congju Li, Michiya Matsusaki   +5 more
wiley   +1 more source

A Rare Complication of Transcatheter Aortic Valve Replacement

JACC: Case Reports, 2019
The authors report the case of an 87-year-old man undergoing transcatheter aortic valve replacement via transfemoral approach who developed a life-threatening complication, i.e., fistulization between the aortic root and the left atrium, which was ...
Severino Iesu, MD, Francesco Vigorito, MD, Giuseppe Iuliano, MD, Paolo Masiello, MD, Rodolfo Citro, MD, PhD   +4 more
doaj  

SynthAorta: A 3D Mesh Dataset of Parametrized Physiological Healthy Aortas [PDF]

arXiv
The effects of the aortic geometry on its mechanics and blood flow, and subsequently on aortic pathologies, remain largely unexplored. The main obstacle lies in obtaining patient-specific aorta models, an extremely difficult procedure in terms of ethics and availability, segmentation, mesh generation, and all of the accompanying processes ...
arxiv  

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source

Wearable Hyperspectral Photoplethysmography Allows Continuous Monitoring of Exercise‐Induced Hypertension

Advanced Science, EarlyView.
A wearable hyperspectral photoplethysmography (HS‐PPG) is reported for continuous blood pressure (BP) monitoring. The HS‐PPG module integrates an ultrathin double‐folded solid immersion grating microspectrometer (DFSIG‐µSPEC), achieving a high spectral resolution of 3.4 nm.
Jung‐Woo Park, Jaehyeok Park, Jaehun Jeon, Seongok Chae, Gi Beom Kim, Geonhui Han, Hyung‐Soon Park, Yong Jeong, Ki‐Hun Jeong   +8 more
wiley   +1 more source

Assessing the Robustness of LLM-based NLP Software via Automated Testing [PDF]

arXiv
Benefiting from the advancements in LLMs, NLP software has undergone rapid development. Such software is widely employed in various safety-critical tasks, such as financial sentiment analysis, toxic content moderation, and log generation. Unlike traditional software, LLM-based NLP software relies on prompts and examples as inputs.
arxiv  

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du, Xu Liu, Jianghua Shen, Hailong Yuan, Hao Zhang, Gan Xi, Yujing Li, Yuhan Wang, Jiahe Zhang, Chaofan Yang, Pengfei Xu, Jiawan Wang, Fang Wang, Siqi Liu, Yanan Zhou, Qi Gu, Jingjing Lu, Tuo Wei, Zeyu Gao, Jingyi Zang, Jun Wang, Moshi Song   +21 more
wiley   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

Advanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu, Canran Gao, Hailing Zhang, Jing Liu, Boxuan Li, Wei Chen, Xiuping Chen, Xue Lin, Ligang Fang, Zhihong Wang   +9 more
wiley   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source