Results 121 to 130 of about 745,128 (377)
An aneurysm is a localized irreversible dilatation of the aortic wall resulting from an alteration of elastic fibers in the media. The main risk is rupture. It depends on the size and growth rate.
Zine el Abidine Benali, Hatim Abdedaim
doaj +1 more source
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu +12 more
wiley +1 more source
The art of aortic valve repairCentral Message
Lars G. Svensson, MD, PhD
doaj +1 more source
Aortic Arch Width and Cardiovascular Disease in Men and Women in the Community
Background We sought to determine whether increased aortic arch width (AAW) adds to standard Framingham risk factors and coronary artery calcium (CAC) for prediction of incident adverse cardiovascular disease (CVD) events in community‐dwelling adults ...
Michael L. Chuang +7 more
doaj +1 more source
Biodegradable Adhesive Systems for Bio‐Integrated Applications
Biodegradable adhesives provide temporary yet reliable adhesion while degrading into safe, non‐toxic by‐products under physiological or environmental conditions. This review summarizes recent developments in physical and chemical adhesion mechanisms—including hydrogen bonding, catechol chemistry, amine‐carboxyl coupling, and emerging diazirine and urea
Won Bae Han +6 more
wiley +1 more source
Association between leaflet fusion pattern and thoracic aorta morphology in patients with bicuspid aortic valve [PDF]
Bryce Merritt +5 more
openalex +1 more source
Unusual echocardiographic finding leading to diagnosis of pulmonary sequestration [PDF]
Pulmonary sequestration is an embryonic mass of non- functioning lung tissue that does not communicate with the tracheobronchial tree and has a reported incidence of 0.15%-6.4% of all the pulmonary malformations.
Arora, R. +3 more
core
Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang +11 more
wiley +1 more source
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi +10 more
wiley +1 more source

