Results 141 to 150 of about 719,506 (384)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Aneurisma de aorta tóraco-abdominal multisacular

open access: yesCirugía del Uruguay, 1985
Se presenta un caso de un paciente de 38 años con aneurisma de aorta tóraco-abdominal, de probable etiología luética que tomaba desde D 10 a· L 2 teniendo unos 10 cm de diámetro en sentido transversal.
Rómulo Danza   +4 more
doaj  

A aorta no centro

open access: yesJornal Vascular Brasileiro, 2023
Andre Brito-Queiroz   +2 more
openaire   +3 more sources

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

open access: yesAdvanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge   +10 more
wiley   +1 more source

Coartación de la aorta

open access: yesCirugía del Uruguay, 1976
Desde 1961 a 1975, 187 pacientes con coartación de aorta torácica han sido operados en este Servicio. Cincuenta y tres eran menores de un ruño de edad y el 86 % de ellos tenían defectos cardíacos asociados.
José V Nozar   +3 more
doaj  

Dissected saccular aneurysms of the ascending aorta

open access: yesClinical Case Reports, 2019
This report highlights the need for distinction between saccular and fusiform aortic aneurysms, considering the high risk of rupture of saccular aneurysms.
Hazem Aljasem, Mohammad Bashar Izzat
doaj   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

open access: yesAdvanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro   +10 more
wiley   +1 more source

Bilateral intralobar pulmonary sequestration : a case report [PDF]

open access: yes, 2009
Bronchopulmonary sequestration is a congenital lung malformation consisting of a non-functioning lung segment. Arterial supply to such a segment is found to be systemic rather than pulmonary, and by definition there is no communication with the ...
Grech, Reuben   +5 more
core  

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

open access: yesAdvanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng   +16 more
wiley   +1 more source

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