Results 151 to 160 of about 735,548 (339)

Aneurisma micótico de la aorta abdominal secundario a infección por Proteus mirabilis [PDF]

open access: diamond, 2019
Martín Vallverdù Scorza   +4 more
openalex   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi   +18 more
wiley   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha   +13 more
wiley   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

open access: yesAdvanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini   +4 more
wiley   +1 more source

Traumatic rupture of the aorta : a case report and discussion of clinical features [PDF]

open access: yes, 2012
A young female patient was involved in a head-on collision and sustained a rupture of the aortic isthmus. She underwent emergency surgical repair of an aortic pseudo-aneurysm with an interposition graft.
Casha, Aaron   +3 more
core  

Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta—Brief Report

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2017
Hisashi Sawada   +4 more
semanticscholar   +1 more source

NIR‐II Responsive Multifunctional Scaffold Enabling “Kill‐Modulation‐Build” Synergistic Therapy for Infectious Bone Defects

open access: yesAdvanced Science, EarlyView.
A novel multifunctional scaffold with photothermal effects is developed for infected bone defect repair. It facilitates angiogenesis and osteogenesis while eliminating bacteria through hyperthermia. Additionally, the scaffold promotes macrophage polarization from M1 to M2 via ROS scavenging, enhancing anti‐inflammatory activity. This study demonstrates
Qifei Yang   +9 more
wiley   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

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