Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
Cross-organ analysis reveals associations between vascular properties of the retina, the carotid and aortic arteries, and the brain. [PDF]
Ortín Vela S, Bergmann S.
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Disseminated melioidosis presenting with multifocal thoracic aortic mycotic aneurysms: A case report. [PDF]
Chang CY +2 more
europepmc +1 more source
Validation of the murine aortic arch as a model to study human vascular diseases [PDF]
Casteleyn, Christophe +6 more
core +1 more source
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song +9 more
wiley +1 more source
Contrast dose determined by body weight and tube potential in coronary CT angiography improves attenuation consistency and reduces contrast dose. [PDF]
Leiknes JB, Dæhli Kurz K, Larsen AI.
europepmc +1 more source
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen +9 more
wiley +1 more source
Intravascular Lithotripsy of Negatively Remodeled Calcified Abdominal Aorta to Facilitate Transfemoral Transcatheter Aortic Valve Replacement. [PDF]
Nishi T +5 more
europepmc +1 more source
Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source

