Results 251 to 260 of about 110,272 (307)

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

The FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

Sirtuin 1 Activation Mitigates Murine Vasculitis Severity by Promoting Mitophagy. [PDF]

Circ Res
Atici AE, Jena PK, Carvalho TT, Ross BL, Aubuchon EA, Lane ME, Gomez AC, Lee Y, Fishbein MC, Azer J, Mesquita T, Chen S, Crother TR, Arditi M, Noval Rivas M.   +14 more
europepmc   +1 more source

When proteases reshape barriers: Basement membrane remodelling in development, wound healing and tumour progression

The FEBS Journal, EarlyView.
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre, Guila Dayan, Patricia Rousselle   +2 more
wiley   +1 more source

Perioperative Outcomes in Factor XI Deficiency: A Systematic Review

Haemophilia, EarlyView.
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni, Raeesah Mohammed, Silvio Ligia, Jim Douketis, Chatree Chai‐Adisaksopha, Alfonso Iorio, Davide Matino   +6 more
wiley   +1 more source

Geometric and mechanical changes along the length of the porcine aorta. [PDF]

J Biomech
Badal RM, Huntley ND, Guan W, Iaizzo PA, Barocas VH.   +4 more
europepmc   +1 more source

Comparing clinical manifestations, treatment strategies and outcomes of Staphylococcus lugdunensis bacteraemia versus Staphylococcus aureus bacteraemia – a retrospective cohort study

Internal Medicine Journal, EarlyView.
Abstract Background Staphylococcus lugdunensis is a coagulase‐negative Staphylococcus that has been increasingly recognised as a significant pathogen capable of causing invasive infections similar to Staphylococcus aureus. Data comparing the clinical manifestations and outcomes of S. lugdunensis bacteraemia to S. aureus bacteraemia remain limited. This
Gemma Webb, Jasmine Choi, Angela Younes, Emily Schembri, Roy Chean, Stephen Guy   +5 more
wiley   +1 more source

Report of a case of renal hilum Castleman disease complicated with Paget's disease of the breast. [PDF]

Front Med (Lausanne)
Yang W, Li H, Shen D, Gu D, Song S, Cui Z.   +5 more
europepmc   +1 more source

A Descriptive Evaluation of Evidence‐Based Rounds in Critical Care Using Mixed Data Types

Journal of Advanced Nursing, EarlyView.
ABSTRACT Objectives To pilot and evaluate the implementation of a structured Evidence‐Based Rounds (EBR) education model in critical care. Design A mixed data type design was used to evaluate Evidence‐Based Rounds in a critical care setting. Structured observational data were captured and open‐ended survey responses were submitted by attendees. Content
P. Yerbury, S. Sutherland, T. Venes, A. Nair, J. Ede   +4 more
wiley   +1 more source

Outcomes of Simultaneous Off-Pump Coronary Artery Bypass Grafting and Vascular Surgery: A Retrospective Case Series. [PDF]

Ann Vasc Dis
Kamata K, Maeda H, Tanaka M.
europepmc   +1 more source

Assessing Quality of Action Research Using the Quality Assessment Action Research Checklist (QuARC): A Hybrid Systematic Narrative Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate the quality of action research studies using the Quality Assessment Action Research Checklist (QuARC) and to assess its utility as a tool for quality appraisal. Design A hybrid systematic narrative review following Turnbull et al.'s six‐stage methodology and reported in accordance with PRISMA 2020 guidance.
Mary Casey, David Coghlan, Áine Carroll, Tom Buckley, Diarmuid Stokes   +4 more
wiley   +1 more source