A noncanonical role for Jagged1 in endothelial mechanotransduction
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez +7 more
wiley +1 more source
Isolated abdominal aortic dissection: Key role of computed tomography in diagnosis and management, and the etiological dilemma (spontaneous vs iatrogenic)-case report. [PDF]
Lissane Eddine S +9 more
europepmc +1 more source
Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley +1 more source
A Descriptive Evaluation of Evidence‐Based Rounds in Critical Care Using Mixed Data Types
ABSTRACT Objectives To pilot and evaluate the implementation of a structured Evidence‐Based Rounds (EBR) education model in critical care. Design A mixed data type design was used to evaluate Evidence‐Based Rounds in a critical care setting. Structured observational data were captured and open‐ended survey responses were submitted by attendees. Content
P. Yerbury +4 more
wiley +1 more source
Delayed Migration of an Amplatzer PFO Occluder to the Infrarenal Abdominal Aorta: Successful Endovascular Snare Retrieval. [PDF]
Cacciapuoti F +4 more
europepmc +1 more source
ABSTRACT Aim To evaluate the quality of action research studies using the Quality Assessment Action Research Checklist (QuARC) and to assess its utility as a tool for quality appraisal. Design A hybrid systematic narrative review following Turnbull et al.'s six‐stage methodology and reported in accordance with PRISMA 2020 guidance.
Mary Casey +4 more
wiley +1 more source
Intraoperative identification and management of renovascular anatomical variations during paraaortic lymphadenectomy: an illustrated surgical experience. [PDF]
Ceylan Ö, Aksel TZ.
europepmc +1 more source
ABSTRACT Background and Aims Transvenous lead extraction (TLE) is increasingly performed for malfunction or infection of cardiac implantable electronic devices (CIED). Active mechanical rotational sheaths facilitate extraction and are available in short and long sizes, but it is unclear how many patients short active mechanical extraction sheaths ...
Caroline Wiederkehr +6 more
wiley +1 more source
Endovascular management for post-dissection aortic aneurysm after prior proximal repair. [PDF]
Li R +7 more
europepmc +1 more source

