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Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth‐leading cause of death globally. Open surgery and endovascular procedures are
Haocheng Lu +6 more
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Delayed Presentation of a Giant Ascending Aortic Aneurysm following Aortic Valve Replacement [PDF]
Case Reports in Medicine, 2009 Giant ascending aortic aneurysm formation following aortic valve replacement is rare. A 28-year-old man who underwent aortic valve replacement with a prosthetic valve for aortic regurgitation secondary to congenital bicuspid aortic valve about 10 years ...
Tugrul Göncü +5 more
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The “bud” of an aortic aneurysm [PDF]
Clinical Case Reports, 2021 AbstractAn overlooked “bud” of an aortic aneurysm on a chest radiography resulted in a saccular aortic aneurysm 9 years later. This eye‐catching image showed us the importance of not only documenting abnormalities in regular radiography but also further imaging evaluation for definitive diagnosis and continuous image follow‐up.
Tetsuo Yamaguchi +3 more
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Pathogenesis and management of abdominal aortic aneurysm
European Heart Journal, 2023 Graphical Abstract Graphical Abstract Potential medical therapies to limit abdominal aortic aneurysm growth or rupture. VSMC, vascular smooth muscle cell; LDL, low density lipoprotein.
J. Golledge +3 more
semanticscholar +1 more source
Cellular senescence and abdominal aortic aneurysm: From pathogenesis to therapeutics
Frontiers in Cardiovascular Medicine, 2022 As China’s population enters the aging stage, the threat of abdominal aortic aneurysm (AAA) mainly in elderly patients is becoming more and more serious.
Ding Wang +11 more
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Frontiers in Physiology, 2022 Background: Abdominal aortic aneurysm (AAA) is a degenerative disease that causes health problems in humans. However, there are no effective drugs for the treatment of AAA. Artemisia annua L. (A.
Longyuan Jia +16 more
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Abdominal Aortic Aneurysm: Roles of Inflammatory Cells
Frontiers in Immunology, 2021 Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas. Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However, inflammation has been considered as a central player in the development of AAA.
Zhen Yuan +5 more
semanticscholar +1 more source
Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection
Frontiers in Cardiovascular Medicine, 2022 Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and fatally. Due to the lack of specific early symptoms, many patients with AAD are often overlooked or misdiagnosed, which is undoubtedly catastrophic for patients.
Xinyu Hao +7 more
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Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm
Circulation, 2021 Supplemental Digital Content is available in the text. Background: Marfan syndrome (MFS) is an autosomal dominant disorder of the connective tissue caused by mutations in the FBN1 (fibrillin-1) gene encoding a large glycoprotein in the extracellular ...
J. Oller +18 more
semanticscholar +1 more source