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Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth‐leading cause of death globally. Open surgery and endovascular procedures are
Haocheng Lu   +6 more
doaj   +2 more sources

Blood pressure, hypertension, and the risk of aortic aneurysm in the UK Biobank [PDF]

open access: yesBMC Cardiovascular Disorders
Background Although an association between elevated blood pressure and risk of aortic aneurysm is established, few studies have investigated the association with aortic aneurysm subtypes.
Rida E.Z. Naqvi   +6 more
doaj   +2 more sources

A case of thoracic aortic aneurysm discovered following poor ventilation during induction of anesthesia [PDF]

open access: yesJA Clinical Reports
Several cases of tracheal stenosis due to thoracic aortic aneurysm have been reported. However, cases of aortic aneurysm discovered following ventilation difficulties immediately after the induction of general anesthesia are rare.
Mahiro Isogai   +4 more
doaj   +2 more sources

Cellular senescence and abdominal aortic aneurysm: From pathogenesis to therapeutics

open access: yesFrontiers in Cardiovascular Medicine, 2022
As China’s population enters the aging stage, the threat of abdominal aortic aneurysm (AAA) mainly in elderly patients is becoming more and more serious.
Ding Wang   +11 more
doaj   +1 more source

Through network pharmacology and molecular docking to explore the underlying mechanism of Artemisia annua L. treating in abdominal aortic aneurysm

open access: yesFrontiers in Physiology, 2022
Background: Abdominal aortic aneurysm (AAA) is a degenerative disease that causes health problems in humans. However, there are no effective drugs for the treatment of AAA. Artemisia annua L. (A.
Longyuan Jia   +16 more
doaj   +1 more source

Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection

open access: yesFrontiers in Cardiovascular Medicine, 2022
Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and fatally. Due to the lack of specific early symptoms, many patients with AAD are often overlooked or misdiagnosed, which is undoubtedly catastrophic for patients.
Xinyu Hao   +7 more
doaj   +1 more source

Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental validation

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveAbdominal aortic aneurysm (AAA) is a lethal peripheral vascular disease. Inflammatory immune cell infiltration is a central part of the pathogenesis of AAA.
Shuai Cheng   +23 more
doaj   +1 more source

The treatment choices of abdominal aortic aneurysm patients in China in the era of value-based healthcare

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundEndovascular aneurysm repair (EVAR) is often seen as the first choice treatment for patients with abdominal aortic aneurysm (AAA), particularly high-risk patients, yet the long-term survival rate and improvement in quality of life are still ...
Liren Duan   +6 more
doaj   +1 more source

Melatonin Plays a Critical Protective Role in Nicotine-Related Abdominal Aortic Aneurysm

open access: yesFrontiers in Physiology, 2020
Aim: Smoking is a major risk factor for abdominal aortic aneurysm (AAA). Among the components of smoke, nicotine is known to exert pro-atherosclerotic, prothrombotic, and proangiogenic effects on vascular smooth muscle cells (VSMCs).
Liren Duan   +9 more
doaj   +1 more source

Outcome after surgical repair of sealed rupture abdominal aortic aneurysms: a case-control study [PDF]

open access: yesClinics, 2006
OBJECTIVE: To establish, in a case-control study, the early mortality and long-term survival after surgical correction of sealed rupture abdominal aortic aneurysm, compared to controls who underwent standard, nonruptured abdominal aortic aneurysm repair.
Telmo Pedro Bonamigo   +5 more
doaj   +1 more source

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