Results 1 to 10 of about 203,989 (258)

Blood pressure, hypertension, and the risk of aortic aneurysm in the UK Biobank [PDF]

BMC Cardiovascular Disorders
Background Although an association between elevated blood pressure and risk of aortic aneurysm is established, few studies have investigated the association with aortic aneurysm subtypes.
Rida E.Z. Naqvi, Ghaliah Baroom, Lili Zheng, Makoto Hibino, Antonio Berlanga-Taylor, Alicia K. Heath, Dagfinn Aune   +6 more
doaj   +2 more sources

Cellular senescence and abdominal aortic aneurysm: From pathogenesis to therapeutics

Frontiers in Cardiovascular Medicine, 2022
As China’s population enters the aging stage, the threat of abdominal aortic aneurysm (AAA) mainly in elderly patients is becoming more and more serious.
Ding Wang, Ding Wang, Xinyu Hao, Xinyu Hao, Longyuan Jia, Longyuan Jia, Yuchen Jing, Yuchen Jing, Bo Jiang, Bo Jiang, Shijie Xin, Shijie Xin   +11 more
doaj   +1 more source

Through network pharmacology and molecular docking to explore the underlying mechanism of Artemisia annua L. treating in abdominal aortic aneurysm

Frontiers in Physiology, 2022
Background: Abdominal aortic aneurysm (AAA) is a degenerative disease that causes health problems in humans. However, there are no effective drugs for the treatment of AAA. Artemisia annua L. (A.
Longyuan Jia, Longyuan Jia, Yuchen Jing, Yuchen Jing, Ding Wang, Ding Wang, Shuai Cheng, Shuai Cheng, Chen Fu, Xiangyu Chu, Xiangyu Chu, Chenye Yang, Chenye Yang, Bo Jiang, Bo Jiang, Shijie Xin, Shijie Xin   +16 more
doaj   +1 more source

Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection

Frontiers in Cardiovascular Medicine, 2022
Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and fatally. Due to the lack of specific early symptoms, many patients with AAD are often overlooked or misdiagnosed, which is undoubtedly catastrophic for patients.
Xinyu Hao, Xinyu Hao, Shuai Cheng, Shuai Cheng, Bo Jiang, Bo Jiang, Shijie Xin, Shijie Xin   +7 more
doaj   +1 more source

Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental validation

Frontiers in Cardiovascular Medicine, 2022
ObjectiveAbdominal aortic aneurysm (AAA) is a lethal peripheral vascular disease. Inflammatory immune cell infiltration is a central part of the pathogenesis of AAA.
Shuai Cheng, Shuai Cheng, Shuai Cheng, Yuanlin Liu, Yuanlin Liu, Yuanlin Liu, Yuchen Jing, Yuchen Jing, Yuchen Jing, Bo Jiang, Bo Jiang, Bo Jiang, Ding Wang, Ding Wang, Ding Wang, Xiangyu Chu, Xiangyu Chu, Xiangyu Chu, Longyuan Jia, Longyuan Jia, Longyuan Jia, Shijie Xin, Shijie Xin, Shijie Xin   +23 more
doaj   +1 more source

The treatment choices of abdominal aortic aneurysm patients in China in the era of value-based healthcare

Frontiers in Cardiovascular Medicine, 2022
BackgroundEndovascular aneurysm repair (EVAR) is often seen as the first choice treatment for patients with abdominal aortic aneurysm (AAA), particularly high-risk patients, yet the long-term survival rate and improvement in quality of life are still ...
Liren Duan, Liren Duan, Wei Xin, Shenli Li, Lin Zhao, Shijie Xin, Shijie Xin   +6 more
doaj   +1 more source

Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the second most prevalent aortic disease following atherosclerosis, representing the ninth‐leading cause of death globally. Open surgery and endovascular procedures are
Haocheng Lu, Wa Du, Lu Ren, Milton H. Hamblin, Richard C. Becker, Y. Eugene Chen, Yanbo Fan   +6 more
doaj   +1 more source

Melatonin Plays a Critical Protective Role in Nicotine-Related Abdominal Aortic Aneurysm

Frontiers in Physiology, 2020
Aim: Smoking is a major risk factor for abdominal aortic aneurysm (AAA). Among the components of smoke, nicotine is known to exert pro-atherosclerotic, prothrombotic, and proangiogenic effects on vascular smooth muscle cells (VSMCs).
Liren Duan, Shenli Li, Lei Wang, Yuchen Jing, Guangxin Li, Yaodong Sun, Weifeng Sun, Yalun Li, Lin Zhao, Shijie Xin   +9 more
doaj   +1 more source

Outcome after surgical repair of sealed rupture abdominal aortic aneurysms: a case-control study [PDF]

Clinics, 2006
OBJECTIVE: To establish, in a case-control study, the early mortality and long-term survival after surgical correction of sealed rupture abdominal aortic aneurysm, compared to controls who underwent standard, nonruptured abdominal aortic aneurysm repair.
Telmo Pedro Bonamigo, Monica Becker, Elton Luiz Schmidt Weber, Cláudia Bianco, Fausto Miranda Jr, Luiz Francisco Poli de Figueiredo   +5 more
doaj   +1 more source

Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression. [PDF]

, 2016
Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli.
Azuma, Junya, Dalman, Ronald L, Deng, Alicia C, Hsu, Mark, Kalish, Flora, Kayama, Yosuke, Maegdefessel, Lars, Morisawa, Takeshi, Spin, Joshua M, Stevenson, David K, Tsao, Philip S, Wallenstein, Matthew B, Wong, Ronald J, Zhao, Hui   +13 more
core   +4 more sources