Results 91 to 100 of about 178,480 (247)

Elucidating the etiology of idiopathic spontaneous intraperitoneal hemorrhage

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Free blood within the abdominal cavity (hemoperitoneum) presents a significant diagnostic and interpretive challenge. It may result from trauma or occur spontaneously in association with underlying disease conditions. When no source of fatal hemorrhage is identified, the implications extend across forensic, criminalistic, legal, and ethical ...
Dalibor Kovařík   +4 more
wiley   +1 more source

Immune Modulation as a Treatment for Abdominal Aortic Aneurysms [PDF]

open access: yes, 2018
In the United States, over 200,000 new patients are diagnosed with abdominal aortic aneurysm (AAA) each year. Consequently, over 40,000 highly morbid aortic reconstructions are performed each year to prevent aneurysm rupture, a catastrophic event ...
Murphy, Michael P., Wang, S. Keisin
core   +1 more source

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease

open access: yesOncoTarget, 2015
Abdominal aortic aneurysm (AAA) and aortic occlusive disease (AOD) represent common causes of morbidity and mortality in elderly populations which were previously believed to have common aetiologies.
E. Biros   +11 more
semanticscholar   +1 more source

Prevalence and impact of additional CHIP mutations in JAK2V617F‐positive ischaemic cerebrovascular patients

open access: yesBritish Journal of Haematology, EarlyView.
Summary The JAK2V617F mutation is associated with increased cardiovascular risk, including ischaemic stroke. This study investigates the prevalence of additional mutations in ischaemic cerebrovascular patients with and without JAK2V617F to better understand the mechanisms contributing to thrombotic risk.
Marie Hvelplund Kristiansen   +5 more
wiley   +1 more source

Metformin and Abdominal Aortic Aneurysm [PDF]

open access: yesEuropean Journal of Vascular and Endovascular Surgery, 2017
Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are ...
openaire   +5 more sources

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin   +6 more
wiley   +1 more source

MFG‐E8 Accelerates Abdominal Aortic Aneurysm Formation by Enhancing ERK MAPK/NOX4 Axis‐Associated Oxidative Stress

open access: yesCell Proliferation, EarlyView.
MFG‐E8 promotes oxidative stress by upregulating NOX4 and activating the MAPK pathway, which increases ROS production and affects vascular smooth muscle cell (VSMC) apoptosis, thereby driving the progression of abdominal aortic aneurysm (AAA). Resveratrol can inhibit the expression and function of MFG‐E8, reduce ROS generation, and lower the incidence ...
Jie Xiao   +6 more
wiley   +1 more source

Individual‐patient meta‐analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm

open access: yesBritish Journal of Surgery, 2015
The benefits of endovascular repair of ruptured abdominal aortic aneurysm remain controversial, without any strong evidence about advantages in specific subgroups.
M. Sweeting   +148 more
semanticscholar   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou   +5 more
wiley   +1 more source

Defining the scope of point‐of‐care ultrasound in internal medicine: a consensus statement by the point‐of‐care special interest group of the Internal Medicine Society of Australia and New Zealand

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Point‐of‐care ultrasound (POCUS) complements physical examination to advance diagnosis and treatment in a range of clinical scenarios. However, the scope for adult internal medicine physicians is not defined in Australia and New Zealand.
Ximena Cid‐Serra   +11 more
wiley   +1 more source

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