Results 111 to 120 of about 42,046 (223)

Ninjurin1 in cardiovascular and vascular biology: From molecular mechanisms to therapeutic opportunities

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley   +1 more source

Antioxidation is a Common Defense Strategy for Different Species Under Mechanical Stress

Advanced Genetics, Volume 7, Issue 1, March 2026.
Mechanical stress‐induced oxidative stress is a universal challenge across species, triggering a conserved antioxidant defense strategy. This perspective delves into the molecular evolutionary logic of this response, comparing mechanisms across plants, microorganisms, and animals to reveal their profound phylogenetic significance.
Feixiang Zhu, Kai Huang
wiley   +1 more source

Ruptured abdominal aortic aneurysm [PDF]

Vascular Medicine, 2016
Umberto G, Rossi, Pierluca, Torcia, Maurizio, Cariati   +2 more
openaire   +2 more sources

Thoracic Ultrasound–Related Management Change: Predictors and the Role of Operator Certification (Secondary Analysis of UltraMAN)

Journal of Clinical Ultrasound, Volume 54, Issue 3, Page 635-641, March/April 2026.
Thoracic ultrasound frequently altered ICU management decisions. Changes were more likely in patients with cardiovascular disease or hypovolemia and occurred independently of operator certification. These findings support the routine use of TUS in critically ill patients, even when performed by less‐experienced but supervised operators.
Jorge E. Lopez Matta, Micah L. A. Heldeweg, Luigi Pisani, Carlos V. Elzo Kraemer, Stefanie Slot, Mark E. Haaksma, Jasper M. Smit, Amne Mousa, Giovanna Magnesa, Fabrizia Massaro, Hugo R. W. Touw, Viviane Schouten, Pieter R. Tuinman, David J. van Westerloo   +13 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Ultrasonography in General Practice: Insights From an Implementation Study in a Low‐Income Neighborhood of Amsterdam

Sonography, Volume 13, Issue 1, March 2026.
ABSTRACT Background Ultrasonography is increasingly being used in primary care settings, facilitated by technological advancements, reduced device‐related costs, and improved access to training and support. It holds particular promise for underserved communities, where barriers such as co‐pays or long waiting lists can limit access to diagnostic ...
Ralf E. Harskamp, Britt Soddemann genaamd Keute, Constantijn Pleiter, Jelle C. L. Himmelreich   +3 more
wiley   +1 more source

The Influence of Bromelain Administration on Pro‐Inflammatory Cytokines and Lipid Peroxidation in a Rat Model of Intestinal Ischemia/Reperfusion Injury

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Bromelain reduces levels of the pro‐inflammatory cytokines TNF‐α, IL‐1β and MDA in intestinal ischemia‐reperfusion injury. Bromelain's effects on cytokines also reduce damage to intestinal tissue.2 ABSTRACT Background Ischemia‐reperfusion injury is a critical problem that can occur following multiple clinical procedures.
Çağrı Gültekin, Serkan Sayiner, Şule Çetinel, Ahmet Özer Şehirli   +3 more
wiley   +1 more source

Dasatinib Produces Lengthy Remissions of Extramedullary Leukemia: A Retrospective Observational Study

European Journal of Haematology, Volume 116, Issue 3, Page 302-310, March 2026.
ABSTRACT Since 2004, patients receiving imatinib with relapse in non‐marrow sites were given dasatinib to preserve control of leukemic marrow. Remissions in CNS and other organs began to be reported and are continuously observed to present. With resistance to one BCR::ABL1 tyrosine kinase inhibitor and sensitivity to a dual BCR::ABL1/SRC inhibitor ...
I. Cunningham, R. A. Fisher, J. Yang, Y. Guo, U. Bommhardt   +4 more
wiley   +1 more source

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

Hepatology Research, Volume 56, Issue 3, Page 302-313, March 2026.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan, Seán R. Millar, Ivan J. Perry, Catherine M. Phillips   +3 more
wiley   +1 more source

Metformin Alters Exercise Training Induced Blood Pressure and Aortic Waveform Adaptations in Adults at Risk for Metabolic Syndrome

The Journal of Clinical Hypertension, Volume 28, Issue 3, March 2026.
ABSTRACT Metformin reduces hyperglycemia and cardiovascular disease risk. However, no study has determined if metformin alters blood pressure and/or aortic waveforms in an exercise intensity dependent manner. We tested if metformin alters blood pressure and aortic waveforms before and during insulin‐stimulation following low and high intensity exercise
Steven K. Malin, Emily M. Heiston, Daniel J. Battillo, Tristan J. Ragland, Ankit M. Shah, James T. Patrie   +5 more
wiley   +1 more source