Causal factors in the development of thoracic aortic aneurysm
Aim. To assess the causal factors in the development of thoracic aortic aneurysm. Despite the existing screening programmes, widely used visualisation methods, and improved intervention techniques, aortic aneurysm remains one of the leading causes of ...
E. B. Luneva +5 more
doaj +1 more source
Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing. [PDF]
The flowchart of the study. BAPN, β‐aminopropionitrile; FUMA, Functional Mapping and Annotation; GO, Gene Ontology; GWAS, genome‐wide association study; KEGG, Kyoto encyclopedia of genes and genomes; LDSC, LD score regression; MR‐JTI, mendelian randomization joint‐tissue imputation; MTAG, multi‐trait analysis of GWAS; siRNA, small interfering RNA ...
Song Q +6 more
europepmc +2 more sources
Elective Open Suprarenal Aneurysm Repair in England from 2000 to 2010 an Observational Study of Hospital Episode Statistics [PDF]
Background: Open surgery is widely used as a benchmark for the results of fenestrated endovascular repair of complex abdominal aortic aneurysms (AAA).
Alan Karthikesalingam +31 more
core +8 more sources
TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc +12 more
core +2 more sources
The AFX2 endovascular repair system is a unibody, bifurcated stent graft that can be used in an abdominal aortic aneurysm associated with anatomical challenges, especially if it is combined with different aortic cuffs.
Panagitsa Christoforou +3 more
doaj +1 more source
Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario +13 more
core +1 more source
Massive thoracic aortic aneurysm [PDF]
A 46 year old man presented to his general practitioner with coryzal symptoms. His practitioner incidentally auscultated a precordial murmur and thus referred the patient for transthoracic echocardiography, which showed left …
K C R, Patel, F, Leyva, R S, Bonser
openaire +2 more sources
Computational fluid dynamicaccuracy in mimicking changes in blood hemodynamics in patients with acute type IIIb aortic dissection treated with TEVAR [PDF]
Background: We aimed to verify the accuracy of the Computational Fluid Dynamics (CFD) algorithm for blood flow reconstruction for type IIIb aortic dissection (TBAD) before and after thoracic endovascular aortic repair (TEVAR).
Domenig, Christoph +5 more
core +1 more source
Still uncertainty about the need for ...
C D, Bicknell, J T, Powell
openaire +2 more sources
Aortocutaneous fistula is an extremely rare complication after aortic endograft infection. We report on the management of a patient who presented with aortocutaneous fistula following emergency endovascular aneurysm repair (EVAR) of an aortoenteric ...
Rahul Ralph Sima +4 more
doaj +1 more source

