Results 21 to 30 of about 24,252 (121)

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Telomere Biology and Thoracic Aortic Aneurysm [PDF]

International Journal of Molecular Sciences, 2017
Ascending aortic aneurysms are mostly asymptomatic and present a great risk of aortic dissection or perforation. Consequently, ascending aortic aneurysms are a source of lethality with increased age. Biological aging results in progressive attrition of telomeres, which are the repetitive DNA sequences at the end of chromosomes.
Thomas Aschacher, Olivia Salameh, Florian Enzmann, Barbara Messner, Michael Bergmann   +4 more
openaire   +3 more sources

Microaxial pump‐supported coronary surgery without CPB to optimize outcome in severely impaired left ventricles

ESC Heart Failure, EarlyView.
Abstract Aims Cardiopulmonary bypass (CPB) is the standard approach for coronary artery bypass grafting (CABG) in advanced ischaemic cardiomyopathy. Microaxial pump support has been envisioned to allow for beating‐heart CABG without CPB (MPCAB), thereby avoiding CPB‐inherent complications.
Anna Kathrin Assmann, Merve Arik‐Doganay, Sebastian Waßenberg, Payam Akhyari, Artur Lichtenberg, Alexander Assmann   +5 more
wiley   +1 more source

Case Series: Natural History and Treatment of Thoracic Aortic Sarcoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Aortic sarcoma is a rare and aggressive malignancy with a poor prognosis despite surgical resection and vascular reconstruction. We present a case series of patients with thoracic aortic sarcoma, highlighting three distinct clinical scenarios: primary resection, resection following prior thoracic aortic endograft, and nonoperative management ...
Calvin L. Chao, Nicola M. Habash, Mark K. Eskandari   +2 more
wiley   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

Molecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez, Antonio Vico‐Padilla, Claus Schneider, Juan Carlos Espín, Antonio González‐Sarrías, Juan Antonio Giménez‐Bastida   +5 more
wiley   +1 more source

Deciphering the panvascular immune landscape of atherosclerosis

VIEW, EarlyView.
Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong, Yifan Chen, Yuehong Wang, Wenhai Pan, Honghao Huang, Lin Lin Cao, Yili Wang, Jiawen Zhang, Yunyi Liang, Xiangyue Qian, Chenxi Shi, Xiyuan Lu, Jun Pu   +12 more
wiley   +1 more source

Radiological Insights Into the Pericardium: A Comprehensive Review

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT The pericardium is not simply a two‐layered membrane surrounding the heart and great vessels. Pericardial effusion is the most common manifestation of various pathological conditions involving the pericardium. Therefore, we are tempted to think of the pericardium as a virtual space containing only fluid, but it can also contain solid and ...
Felipe Aluja‐Jaramillo, Omar Andrés Pantoja‐Burbano, Fernando R. Gutiérrez, Carlos Previgliano, Sanjeev Bhalla   +4 more
wiley   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott, Videha Sharma, Jessica Keen, William Gerard Newman   +3 more
wiley   +1 more source

Pre‐operative reference ranges for ROTEM® sigma in patients undergoing cardiac surgery: a secondary analysis of two prospective trial cohorts

Anaesthesia, EarlyView.
Summary Introduction Rotational thromboelastometry (ROTEM®) is used widely in cardiac surgery. Reference ranges are derived from healthy volunteers but may not be interchangeable with those from patients undergoing cardiac surgery. Furthermore, sex and age seem to influence rotational thromboelastometry profiles.
Maite M. T. van Haeren, Meike Brouwers, Jimmy Schenk, Jennifer S. Breel, Sijm H. Noteboom, Eline Kho, Susanne Eberl, Denise P. Veelo, Alexander P. J. Vlaar, Marcella C. A. Müller, Henning Hermanns   +10 more
wiley   +1 more source

Outcomes of type A aortic dissection in Australia

ANZ Journal of Surgery, EarlyView.
Mortality outcomes for type A aortic dissection in Australia have improved over time, stabilizing at 18% over the last 5 years. Units performing fewer operations for type A dissection showed equivalent mortality outcomes to high‐volume units. Abstract Introduction Without surgical intervention, type A aortic dissection (TAAD) carries a high risk of ...
Abbey Knox, Damian Gimpel, David Lance, Gregory D. Rice, Gareth Crouch, Richard F. Newland, Robert A. Baker, Jayme S. Bennetts   +7 more
wiley   +1 more source