Results 41 to 50 of about 49,570 (218)

Secondary aortoesophageal fistula after thoracic endovascular aortic repair for a huge aneurysm

open access: yesDiagnostic and Interventional Radiology, 2013
Thoracic endovascular aortic repair for a descending thoracic aortic aneurysm is an excellent alternative to open surgery, especially in patients with a number of comorbidities.
Akhmadu Muradi   +6 more
doaj   +1 more source

Gene knockdown of angiopoietin-like protein 3 reduces the occurrence and development of thoracic aortic aneurysms [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To explore the role of angiopoietin-like protein 3 (ANGPTL3) in the development of thoracic aortic aneurysm (TAA) and its possible mechanism. Methods The TAA patients who underwent open surgical repair in Beijing Anzhen Hospital were selected
YU Hua-hui, JIAO Xiao-lu, YANG Yun-yun, LI Fan, SUN Qiu-ju, YU Yu, LYU Qian-wen, QIN Yan-wen
doaj  

Hybrid endovascular operation for ruptured thoracic aortic aneurysm [PDF]

open access: yes, 2007
The rupture of a thoracic aortic aneurysm is a life-threatening emergency. Conventional open surgical repair carries a high mortality and morbidity. We report an elderly patient who suffered from rupture of a proximal descending thoracic aortic aneurysm ...
Cheng, SWK   +4 more
core  

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

open access: yes, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J   +5 more
core   +3 more sources

Thoracic and Abdominal Aortic Aneurysms [PDF]

open access: yesCirculation, 2005
Aneurysms of the aorta are at times evaluated and treated by physicians from a number of specialties. Indeed, whereas cardiac surgeons operate on the ascending aorta and arch and vascular surgeons manage abdominal aortic aneurysms, at present the responsibility often falls to cardiologists to oversee the medical care of patients with aortic disease of ...
openaire   +2 more sources

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

open access: yesAdvanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu   +7 more
wiley   +1 more source

INFLUENCE OF CARDIOVASCULAR RISK FACTORS ON AORTIC WALL MOTION AFTER REPAIR OF TYPE A AORTIC DISSECTION: AN ECG-GATED CT STUDY [PDF]

open access: yes, 2012
OBJECTIVES: To evaluate aortic shape changes during cardiac cycle with dynamic computed tomographic angiography at important thoracic aorta anatomic landmarks in patients who previously underwent ascending aorta repair because of type A dissection, and ...
CROCCIA, MARIAGRAZIA
core  

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model [PDF]

open access: yes, 2017
Aortic valve disease (AVD) is a common condition with a progressive natural history, and presently, there are no pharmacologic treatment strategies. Elastic fiber fragmentation (EFF) is a hallmark of AVD, and increasing evidence implicates developmental ...
Aikawa   +45 more
core   +2 more sources

Natural history of thoracic aortic aneurysms [PDF]

open access: yesJournal of Vascular Surgery, 2012
Understanding the natural history of thoracic aortic aneurysms (TAAs) is essential to patient care and surgical decision making. In this evidence summary we discuss some of the most clinically relevant features of the disease. The true incidence of TAAs is likely to be higher than currently reported because of the inherently silent nature of TAAs ...
John A. Elefteriades   +2 more
openaire   +2 more sources

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen   +18 more
wiley   +1 more source

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