Results 171 to 180 of about 742,427 (349)

A Standard Operating Procedure for Protein Extraction From Abdominal Aortic Aneurysm Tissue: Enhancing Proteomics Applications

open access: yesPROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose The identification of putative biomarkers for AAA can be achieved through shotgun proteomics. However, tissue heterogeneity hampers its reproducible homogenization and protein extraction. Thus, we aimed to optimize a protocol to maximize protein yield and develop an SOP to foster reproducibility and accelerate translation of proteomics
Telmo Baltazar   +38 more
wiley   +1 more source

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. [PDF]

open access: yes, 2019
People heterozygous for an activating mutation in protein kinase G1 (PRKG1, p.Arg177Gln) develop thoracic aortic aneurysms and dissections (TAAD) as young adults.
Boss, Gerry R   +15 more
core   +1 more source

Target Trial Emulation of Beta‐Blockers After Diagnosis of Colorectal Polyps—Beneficial in Women

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims Beta‐blockers are successfully used to treat hemangioma and may decrease the proliferation of cancer cells. We hypothesized that individuals with colorectal polyps may also benefit from beta‐blocker initiation. Methods Individuals diagnosed with their first colorectal polyp 2006–2016 in the nationwide Swedish ESPRESSO ...
Louise Emilsson   +3 more
wiley   +1 more source

Results of the endovascular abdominal aortic aneurysm repair using the Anaconda aortic endograft [PDF]

open access: bronze, 2014
Antonio Freyrie   +7 more
openalex   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

open access: yesVIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu   +8 more
wiley   +1 more source

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