Results 21 to 30 of about 742,427 (349)

Immune and inflammatory mechanisms of abdominal aortic aneurysm

Frontiers in Immunology, 2022
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-mediated infiltration and a destruction of the aortic wall during AAA development plays significant role in the pathogenesis of this disease.
A. C. Márquez-Sánchez, E. Koltsova
semanticscholar   +1 more source

Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection

Frontiers in Cardiovascular Medicine, 2022
Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and fatally. Due to the lack of specific early symptoms, many patients with AAD are often overlooked or misdiagnosed, which is undoubtedly catastrophic for patients.
Xinyu Hao, Xinyu Hao, Shuai Cheng, Shuai Cheng, Bo Jiang, Bo Jiang, Shijie Xin, Shijie Xin   +7 more
doaj   +1 more source

Abdominal Aortic Aneurysm: Roles of Inflammatory Cells

Frontiers in Immunology, 2021
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas. Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However, inflammation has been considered as a central player in the development of AAA.
Zhen Yuan, Yi Lu, Jia Wei, Jiaqi Wu, Jin Yang, Zhejun Cai   +5 more
semanticscholar   +1 more source

Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental validation

Frontiers in Cardiovascular Medicine, 2022
ObjectiveAbdominal aortic aneurysm (AAA) is a lethal peripheral vascular disease. Inflammatory immune cell infiltration is a central part of the pathogenesis of AAA.
Shuai Cheng, Shuai Cheng, Shuai Cheng, Yuanlin Liu, Yuanlin Liu, Yuanlin Liu, Yuchen Jing, Yuchen Jing, Yuchen Jing, Bo Jiang, Bo Jiang, Bo Jiang, Ding Wang, Ding Wang, Ding Wang, Xiangyu Chu, Xiangyu Chu, Xiangyu Chu, Longyuan Jia, Longyuan Jia, Longyuan Jia, Shijie Xin, Shijie Xin, Shijie Xin   +23 more
doaj   +1 more source

Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm

Circulation, 2021
Supplemental Digital Content is available in the text. Background: Marfan syndrome (MFS) is an autosomal dominant disorder of the connective tissue caused by mutations in the FBN1 (fibrillin-1) gene encoding a large glycoprotein in the extracellular ...
J. Oller, E. Gabandé-Rodríguez, M. J. Ruíz-Rodríguez, Gabriela Desdín-Micó, J. Aranda, R. Rodrigues-Díez, C. Ballesteros-Martínez, E. Blanco, R. Roldán-Montero, P. Acuña, A. Forteza Gil, C. Martín-López, J. Nistal, C. L. Lino Cardenas, M. Lindsay, J. Martín-Ventura, A. Briones, Juan Miguel Redondo, M. Mittelbrunn   +18 more
semanticscholar   +1 more source

The treatment choices of abdominal aortic aneurysm patients in China in the era of value-based healthcare

Frontiers in Cardiovascular Medicine, 2022
BackgroundEndovascular aneurysm repair (EVAR) is often seen as the first choice treatment for patients with abdominal aortic aneurysm (AAA), particularly high-risk patients, yet the long-term survival rate and improvement in quality of life are still ...
Liren Duan, Liren Duan, Wei Xin, Shenli Li, Lin Zhao, Shijie Xin, Shijie Xin   +6 more
doaj   +1 more source

Melatonin Plays a Critical Protective Role in Nicotine-Related Abdominal Aortic Aneurysm

Frontiers in Physiology, 2020
Aim: Smoking is a major risk factor for abdominal aortic aneurysm (AAA). Among the components of smoke, nicotine is known to exert pro-atherosclerotic, prothrombotic, and proangiogenic effects on vascular smooth muscle cells (VSMCs).
Liren Duan, Shenli Li, Lei Wang, Yuchen Jing, Guangxin Li, Yaodong Sun, Weifeng Sun, Yalun Li, Lin Zhao, Shijie Xin   +9 more
doaj   +1 more source

Elective Open Suprarenal Aneurysm Repair in England from 2000 to 2010 an Observational Study of Hospital Episode Statistics [PDF]

, 2013
Background: Open surgery is widely used as a benchmark for the results of fenestrated endovascular repair of complex abdominal aortic aneurysms (AAA).
Alan Karthikesalingam, Alberto Vidal-Diez, Benjamin O. Patterson, CD Bicknell, CS Cina, E Choke, FA Lederle, GH Martin, Giuseppe Sollazzo, GL Gilling-Smith, J Cross, JA Cowan Jr, JA Cowan Jr, Jan D. Poloniecki, JC Parodi, JL De Bruin, JM Hacking, JM Richards, JN Armitage, Matthew M. Thompson, Peter J. E. Holt, Peter Whittaker, PJ Holt, PJ Holt, PJ Holt, RM Greenhalgh, Robert J. Hinchliffe, S Sinha, S Tsai, TP Sarac, V Jongkind, VI Patel   +31 more
core   +5 more sources

Outcome after surgical repair of sealed rupture abdominal aortic aneurysms: a case-control study [PDF]

Clinics, 2006
OBJECTIVE: To establish, in a case-control study, the early mortality and long-term survival after surgical correction of sealed rupture abdominal aortic aneurysm, compared to controls who underwent standard, nonruptured abdominal aortic aneurysm repair.
Telmo Pedro Bonamigo, Monica Becker, Elton Luiz Schmidt Weber, Cláudia Bianco, Fausto Miranda Jr, Luiz Francisco Poli de Figueiredo   +5 more
doaj   +1 more source

Applying modified external aortic root support for treatment of ascending thoracic aorta aneurism and type II aortic dissection in an elderly patient: A case report study

Annals of Vascular Surgery - Brief Reports and Innovations, 2023
The ascending thoracic aortic aneurysm, when combined with aortic dissection, led to a critical medical condition requiring emergent and suitable action.
Mohammadhosein Akhlaghpasand, Setayesh Farahani, Sam-Zeraatian Nejad, Ida Mohammadi, Foolad Eghbali   +4 more
doaj   +1 more source