Results 311 to 320 of about 742,427 (349)

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

British Journal of Pharmacology, Volume 182, Issue 23, Page 5706-5733, December 2025.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy, Miles J. De Blasio, Owen L. Woodman, Pasquale Maffia, Hong Yong Peh, Cheng Xue Qin   +5 more
wiley   +1 more source

Novel Multidisciplinary Cardiometabolic Prehabilitation for Inoperable Aortic Aneurysm Management. [PDF]

JACC Case Rep
Lovell TT, Arulalan SL, Ahmed IA, Annie F, Rodgers-Fischl PMF, Jadue Tobar AJ, Chockalingam A.   +6 more
europepmc   +1 more source

Repurposing colchicine for reduction of residual inflammatory risk in type 1 diabetes: Design and rationale of the REC1TE trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 6884-6893, December 2025.
Abstract Aims Compared to people without diabetes, individuals with type 1 diabetes have a several‐fold increased risk of cardiovascular (CV) morbidity and mortality despite guideline‐recommended management of traditional risk factors; so‐called residual CV risk.
David S. Mathiesen, Josefine V. Hansen, Aske Høck, Casper K. Nielsen, Miriam G. Pedersen, Peter L. Kristensen, Henrik U. Andersen, Marie Louise Aarestrup, Julie L. Forman, Jonatan I. Bagger, Thomas F. Dejgaard, Filip K. Knop, Nicklas J. Johansen, Asger B. Lund   +13 more
wiley   +1 more source

Prophylactic mesh reinforcement after open aortic aneurysm repair: a prospective cohort study. [PDF]

Front Surg
Sguinzi R, Lagger M, Chevalley T, Gremaud B, Menth M, Buhler L, Adamina M.   +6 more
europepmc   +1 more source

Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
The flowchart of the study. BAPN, β‐aminopropionitrile; FUMA, Functional Mapping and Annotation; GO, Gene Ontology; GWAS, genome‐wide association study; KEGG, Kyoto encyclopedia of genes and genomes; LDSC, LD score regression; MR‐JTI, mendelian randomization joint‐tissue imputation; MTAG, multi‐trait analysis of GWAS; siRNA, small interfering RNA ...
Qingyang Song, Tongxin Chu, Quan Liu, Rennan Weng, Huayang Li, Mengya Liang, Zhongkai Wu   +6 more
wiley   +1 more source

The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections. [PDF]

Front Cardiovasc Med
Ma G, Li Y, Jia F.
europepmc   +1 more source

CD8+ T Cells Negatively Modulate Ischemia‐Induced Angiogenesis in Mice

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
Graphical illustration of the mechanism of CD8+ T‐cells/IFN‐γ axis‐mediated angiogenesis in response to ischemic stress. CD8+ T‐cell functions as an important mediator of ischemia‐induced angiogenesis via the modulation of inflammation, oxidative stress, proteolysis, and endothelial proliferation that might be mediated by the IFN‐γ/NLRp3‐caspase‐1 and ...
Xianji Piao, Jin Jingyuan, Longzhu Dai, Longguo Zhao, Yanglong Li, Megumi Narisawa, Shangzhi Shu, Yanna Lei, Xueling Yue, Jinshun Piao, Chengjie Zhu, Lina Hu, Qingsong Cui, Xian Wu Cheng   +13 more
wiley   +1 more source

Overexpression of αVβ3 Integrin in an Aortic Aneurysm Murine Model: Confirmation in <i>Ex Vivo</i> Human Abdominal Aortic Aneurysm Tissue and Its Potential Application for Molecular Imaging Characterisation. [PDF]

EJVES Vasc Forum
Anaya-Ayala JE, Galicia-Vega BJ, Mejía-Cervantes J, Solano-Mendivil E, Landero-Aguilar IA, Marquina-Castillo B, Bravo-Reyna C, Serrano-Gavuzzo C, Medina-Velázquez LA, Hinojosa CA.   +9 more
europepmc   +1 more source

Correction: Deciphering the causal association and underlying transcriptional mechanisms between telomere length and abdominal aortic aneurysm. [PDF]

Front Immunol
Zhang J, Xia X, He S.
europepmc   +1 more source