Results 31 to 40 of about 646,459 (345)

The mechanism and therapy of aortic aneurysms

open access: yesSignal Transduction and Targeted Therapy, 2023
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture.
Jianing Gao   +7 more
doaj   +1 more source

Cellular Mechanisms of Aortic Aneurysm Formation.

open access: yesCirculation Research, 2019
Aortic aneurysms are a common vascular disease in Western populations that can involve virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than thoracic aortic aneurysms and combined they account for >25 000 deaths in the ...
Raymundo A. Quintana, W. Robert Taylor
semanticscholar   +1 more source

MULTIDETECTOR COMPUTED TOMOGRAPHY FOR IDENTIFICATION OF INSTABILITY OF AORTIC ANEURYSM WALL

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Background: Aortic aneurysm is characterized by high incidence, polymorphic clinical features and sudden onset of severe complications.Aim: To develop a standard multidetector computed tomography (MDCT) protocol for aortic aneurysm examination and image ...
M. V. Vishnyakova Jr.   +3 more
doaj   +1 more source

Open versus Endovascular Repair of Abdominal Aortic Aneurysm.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Elective endovascular repair of an abdominal aortic aneurysm results in lower perioperative mortality than traditional open repair, but after 4 years this survival advantage is not seen; in addition, results of two European trials have shown ...
F. Lederle   +7 more
semanticscholar   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet   +9 more
wiley   +1 more source

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2019
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood vessel degenerates, leading to dilation and eventually vessel wall rupture.
Ploingarm Petsophonsakul   +9 more
semanticscholar   +1 more source

Causal factors in the development of thoracic aortic aneurysm

open access: yesРоссийский кардиологический журнал, 2013
Aim. To assess the causal factors in the development of thoracic aortic aneurysm. Despite the existing screening programmes, widely used visualisation methods, and improved intervention techniques, aortic aneurysm remains one of the leading causes of ...
E. B. Luneva   +5 more
doaj   +1 more source

Effect of Doxycycline on Aneurysm Growth Among Patients With Small Infrarenal Abdominal Aortic Aneurysms: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2020
Importance Abdominal aortic aneurysms affect more than 3% of US older adults. Objective To test whether doxycycline reduces the growth of abdominal aortic aneurysm over 2 years as measured by maximum transverse diameter.
B. Baxter   +9 more
semanticscholar   +1 more source

Abdominal aortic aneurysms

open access: yesNature Reviews Disease Primers, 2018
An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a multifactorial disease, and genetic and environmental factors play a part; smoking, male sex and a positive family history are the most important risk factors, and AAA is most common in men >65 years of age.
Rebecka Hultgren   +11 more
openaire   +5 more sources

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

open access: yesExperimental and Molecular Medicine, 2019
Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or endovascular repair (EVAR) is the only effective treatment for aortic aneurysm ...
Sayantan Jana   +3 more
semanticscholar   +1 more source

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