Results 41 to 50 of about 646,459 (345)
Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection
Pharmaceuticals, 2019 Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD) is a life-threatening aortic pathology associated with high morbidity and mortality.
E. M. Maguire +4 more
semanticscholar +1 more source
Aortic valve and aneurysms [PDF]
European Heart Journal, 2015 Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast ![Graphic][1] The aorta is the highway in the human circulation, and accordingly any functional or structural change is associated with severe symptoms or even a fatal outcome. The aortic valve is the door to the aorta and it opens up to 3 billion times in a lifetime.
openaire +3 more sources
Traumatic Aortic Aneurysms [PDF]
Circulation, 1954 Aneurysm of the thoracic aorta may follow severe, nonpenetrating injuries of the thorax unaccompanied by rib fractures. The aneurysms characteristically appear in the first portion of the descending aorta or less commonly in the proximal ascending portion. A large aneurysm, progressive enlargement, or symptoms may necessitate excision or repair.
Hu A. Blake +3 more
openaire +3 more sources
Long telomeres in blood leukocytes are associated with a high risk of ascending aortic aneurysm. [PDF]
PLoS ONE, 2012 Ascending aortic aneurysm is a connective tissue disorder. Even though multiple novel gene mutations have been identified, risk profiling and diagnosis before rupture still represent a challenge.
Tuija J Huusko +7 more
doaj +1 more source
International Journal of Environmental Research and Public Health, 2018 Abdominal aortic aneurysm (AAA) represents an important public health problem with a prevalence between 1.3% and 12.5%. Several population-based randomized trials have evaluated ultrasound screening for AAA providing evidence of a reduction in aneurysm ...
E. Altobelli +3 more
semanticscholar +1 more source
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.
JCI Insight, 2018 Proteoglycan accumulation is a hallmark of medial degeneration in thoracic aortic aneurysm and dissection (TAAD). Here, we defined the aortic proteoglycanome using mass spectrometry, and based on the findings, investigated the large aggregating ...
Frank S. Cikach +10 more
semanticscholar +1 more source
Frontiers in Physiology, 2017 Bicuspid aortic valve (BAV) can be both sporadic and hereditary, is phenotypically variable, and genetically heterogeneous. The clinical presentation of BAV is diverse and commonly associated with a high prevalence of valvular dysfunction producing ...
Elizabeth Norton, Bo Yang
doaj +1 more source
Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study
British medical journal, 2018 Objective To investigate whether oral fluoroquinolone use is associated with an increased risk of aortic aneurysm or dissection. Design Nationwide historical cohort study using linked register data on patient characteristics, filled prescriptions, and ...
B. Pasternak +2 more
semanticscholar +1 more source
Men's Health Journal, 2020 Background: Aortic aneurysm is one of the most common cardiovascular diseases that can lead to numerous challenges for patients. The mortality rate of ruptured Thoracic Aortic Aneurysm (TAA) is observed to be high.
Mohammad Zahedi +7 more
doaj +1 more source
H19 Induces Abdominal Aortic Aneurysm Development and Progression
Circulation, 2018 Background: Long noncoding RNAs have emerged as critical molecular regulators in various biological processes and diseases. Here we sought to identify and functionally characterize long noncoding RNAs as potential mediators in abdominal aortic aneurysm ...
Daniel Y. Li +22 more
semanticscholar +1 more source