Results 41 to 50 of about 114,095 (208)
Advanced Science, EarlyView.This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan +11 more
wiley +1 more source
Theoretical impact of insecticide-impregnated school uniforms on dengue incidence in Thai children. [PDF]
, 2013 BACKGROUND: Children carry the main burden of morbidity and mortality caused by dengue. Children spend a considerable amount of their day at school; hence strategies that reduce human-mosquito contact to protect against the day-biting habits of Aedes ...
Amaku, Marcos +4 more
core +2 more sources
Advanced Science, EarlyView.LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao +7 more
wiley +1 more source
Sarcopenia ‘made simple’ and outcomes from emergency laparotomy
ANZ Journal of Surgery, Volume 92, Issue 12, Page 3198-3203, December 2022., 2022 CT‐assessed ratio of L3 vertebral body cross‐sectional area to total psoas muscle cross‐sectional area (L3:PM) is a simple yet significant predictor of 30‐, 90‐ and 365‐day mortality in emergency laparotomy patients. This study is the first to describe the association in an Australian population.
Yan Joyce Ming +4 more
wiley +1 more source
Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection
Advanced Science, EarlyView.The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng +10 more
wiley +1 more source
ANZ Journal of Surgery, Volume 92, Issue 12, Page 3154-3161, December 2022., 2022 Analysis of multi‐institutional data and benchmarking is an accepted accreditation standard in cardiac surgery. Such a database does not exist for congenital cardiac surgery in Australia and New Zealand (ANZ). To fill this gap, the ANZ Congenital Outcomes Registry for Surgery (ANZCORS) was established in 2017.
Supreet P. Marathe +8 more
wiley +1 more source
Combined transbrachial and transfemoral strategy to deploy an iliac branch endoprosthesis in the setting of a pre-existing endovascular aortic aneurysm repair [PDF]
, 2019 This article describes brachial access to position a long sheath in the abdominal aorta in conjunction with a large caliber sheath via the femoral artery ipsilateral to the target site to deliver a 0.018 bodyfloss wire.
Donde, Nikunj N. +5 more
core +1 more source
Comparison of existing aneurysm models and their path forward [PDF]
, 2020 The two most important aneurysm types are cerebral aneurysms (CA) and abdominal aortic aneurysms (AAA), accounting together for over 80\% of all fatal aneurysm incidences. To minimise aneurysm related deaths, clinicians require various tools to accurately estimate its rupture risk. For both aneurysm types, the current state-of-the-art tools to evaluate
arxiv +1 more source
Fenestrated Endovascular Aneurysm Repair versus Snorkel Endovascular Aneurysm Repair: Competing yet Complementary Strategies. [PDF]
, 2019 Juxtarenal/pararenal aortic aneurysms and type IV thoracoabdominal aneurysms pose particular technical challenges for endovascular repair as they involve the visceral segment in addition to insufficient infrarenal neck for the use of standard ...
Yoon, William J
core +1 more source
Generation of Patient-specific Structured Hexahedral Mesh of Aortic Aneurysm Wall [PDF]
arXiv, 2022 Abdominal Aortic Aneurysm (AAA) is an enlargement in the lower part of the main artery Aorta by 1.5 times its normal diameter. AAA can cause death if rupture occurs. Elective surgeries are recommended to prevent rupture based on geometrical measurements of AAA diameter and diameter growth rate.
arxiv