Inhibition of Nuclear Factor of Activated T-Cells (NFAT) Suppresses Accelerated Atherosclerosis in Diabetic Mice [PDF]
OBJECTIVE OF THE STUDY: Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated
Andersson, AM +11 more
core +1 more source
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming +14 more
wiley +1 more source
Different techniques of distal aortic repair in acute type A dissection: impact on late aortic morphology and reoperation [PDF]
Objective: To compare three different techniques of distal aortic repair in acute type A (de Bakey type I) aortic dissection and to evaluate their impact on the late morphology of the aortic arch and descending aorta and on the incidence of reoperation ...
Althaus, U. +6 more
core
Aortic Coarctation: Recent Developments in Experimental and Computational Methods to Assess Treatments for this Simple Condition [PDF]
Coarctation of the aorta (CoA) is often considered a relatively simple disease, but long-term outcomes suggest otherwise as life expectancies are decades less than in the average population and substantial morbidity often exists.
Feinstein, Jeffrey A. +2 more
core +2 more sources
Pre‐oviposition development of the brown anole (Anolis sagrei)
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling +9 more
wiley +1 more source
Surgical treatment strategies for patients with type A aortic dissection involving arch anomalies [PDF]
Jiade Zhu +14 more
openalex +1 more source
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff +6 more
wiley +1 more source
We report a case of a 72-year-old female with a right aortic arch with mirror-image branching of arch vessels presenting with dysphagia, and characteristic images on barium esophagogram, contrast-enhanced computed tomography scan, and magnetic resonance ...
Guneet Singh +3 more
doaj +1 more source
Aortic arch reconstruction in newborns with an autologous pericardial patch: contemporary results [PDF]
Massimo Bernabei +5 more
openalex +1 more source
Double aortic arch diagnosed in a 44-year-old woman with recurring respiratory infections [PDF]
Complete vascular rings are originated because of the persistence of the fourth aortic arches, which surround the trachea and esophagus partially or completely, compressing them.
Fernández Tena, Ana +1 more
core +3 more sources

