Results 201 to 210 of about 73,026 (266)

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

open access: yesPhytotherapy Research, Volume 40, Issue 11, Page 6670-6684, November 2026.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao   +6 more
wiley   +1 more source

Complete Surgical Resection of Rare Solitary Anterior Mediastinal Metastasis From Ovarian Clear Cell Carcinoma

open access: yesRespirology Case Reports, Volume 14, Issue 11, November 2026.
Here, we report an extremely rare case of a solitary anterior mediastinal metastasis from ovarian clear cell carcinoma. The lesion was successfully managed with complete R0 surgical resection via median sternotomy. In patients with a history of ovarian clear cell carcinoma, aggressive surgical intervention should be considered for isolated thoracic ...
Teruhisa Chiba   +6 more
wiley   +1 more source

Scimitar Syndrome in Adolescence

open access: yesRespirology Case Reports, Volume 14, Issue 11, November 2026.
Scimitar syndrome may present beyond infancy with non‐specific respiratory symptoms. Chest radiography and CT demonstrated right lung hypoplasia, cardiac dextroposition, associated bronchovascular anomalies and anomalous pulmonary venous drainage into the inferior vena cava, establishing the diagnosis.
Shan Kai Ing   +4 more
wiley   +1 more source

Sequential Arch-Tear Eligibility for Uncovered Aortic Arch Stent in Acute DeBakey Type I Aortic Dissection. [PDF]

open access: yesJ Cardiovasc Dev Dis
Petrone D   +9 more
europepmc   +1 more source

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