Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao +6 more
wiley +1 more source
Compressed Branching Geometry in a Bovine-Type Aortic Arch: A Morphometric Cadaveric Case Report and Systematic Review of the Literature. [PDF]
Naoun AA, Figueroa Monsanto HL, Veras W.
europepmc +1 more source
Here, we report an extremely rare case of a solitary anterior mediastinal metastasis from ovarian clear cell carcinoma. The lesion was successfully managed with complete R0 surgical resection via median sternotomy. In patients with a history of ovarian clear cell carcinoma, aggressive surgical intervention should be considered for isolated thoracic ...
Teruhisa Chiba +6 more
wiley +1 more source
Tailored anesthetic management using advanced hemodynamic and cerebral monitoring during urgent aortic arch endovascular repair. [PDF]
Pulitanò R +3 more
europepmc +1 more source
Scimitar Syndrome in Adolescence
Scimitar syndrome may present beyond infancy with non‐specific respiratory symptoms. Chest radiography and CT demonstrated right lung hypoplasia, cardiac dextroposition, associated bronchovascular anomalies and anomalous pulmonary venous drainage into the inferior vena cava, establishing the diagnosis.
Shan Kai Ing +4 more
wiley +1 more source
Sequential Arch-Tear Eligibility for Uncovered Aortic Arch Stent in Acute DeBakey Type I Aortic Dissection. [PDF]
Petrone D +9 more
europepmc +1 more source
Congenital Absence of the Left Pulmonary Artery Associated With Right-Sided Aortic Arch Presenting as Hemoptysis in an Adult: A Case Report. [PDF]
Kauser T +6 more
europepmc +1 more source
Adult-onset diagnosis of interrupted aortic arch presenting with uncontrolled hypertension. [PDF]
Zheng R, Yagi S, Sata M.
europepmc +1 more source
Quantitative CT Geometry of the Patent Ductus Arteriosus in Infants with Congenital Heart Disease: Association with Aortic Arch Obstruction or Hypoplasia. [PDF]
Pop M +6 more
europepmc +1 more source
Can the beating heart be advantageous during aortic arch replacement using frozen elephant trunk? [PDF]
Sef D, Sef D, Luthra S.
europepmc +1 more source

