Results 81 to 90 of about 73,026 (266)

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman   +7 more
wiley   +1 more source

Arch translocation and the intra-arch elephant-trunk technique with collared graft for extended chronic dissecting aortic aneurysm

open access: yesJournal of Cardiothoracic Surgery, 2013
Management of extensive, chronic, dissecting aortic aneurysms after prior repair of the ascending aorta presents a technical challenge for surgeons.
Ikenaga Shigeru   +5 more
doaj   +1 more source

Preoperative Prediction of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma Using Arterial Enhancement Fraction Derived From Dual‐Layer Spectral CT

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of arterial enhancement fraction (AEF) derived from dual‐layer detector spectral CT (DLCT) in preoperative assessment of cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC), and to compare its performance with other spectral CT quantitative parameters and conventional CT ...
Lili Ye   +6 more
wiley   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

open access: yesiNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu   +3 more
wiley   +1 more source

Combined Karyotyping, Copy Number Variation Sequencing, and Whole Exome Sequencing in the Prenatal Diagnosis of Congenital Heart Disease: Detection Rates and Phenotypic Associations

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study combined karyotyping, copy number variation sequencing, and whole‐exome sequencing to assess the value of genetic testing in the prenatal diagnosis of congenital heart disease (CHD) and to evaluate the relationship between genetic variants and prenatal phenotypes.
Jieqiong Xie   +7 more
wiley   +1 more source

Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background E‐cigarettes contribute to endothelial dysfunction, a known cause of systemic atherosclerotic disease that cannot be adequately characterized by a single physiological parameter measured at a single vascular bed. Purpose/Hypothesis Quantify and compare acute effects of smoking or vaping with tobacco cigarettes (t‐cigs), nicotinized ...
Marianne Nabbout   +9 more
wiley   +1 more source

Structural Covariance Analysis of Altered Brain Development in Neonates With Congenital Heart Disease After Surgery

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Brain development is altered in neonates with congenital heart disease (CHD), with well‐characterised reductions in regional brain volumes and enlargement of CSF spaces. However, perioperative morphological changes remain incompletely understood. Purpose To identify brain regions showing spatial patterns of coordinated expansion and
Mirthe E. M. van der Meijden   +14 more
wiley   +1 more source

Transaortic Transcatheter Aortic Valve Replacement With Bicuspid Aortic Valve Stenosis and Circumflex Aortic Arch

open access: yesClinical Case Reports
Circumflex aortic arch is a rare congenital anomaly. This case describes transcatheter aortic valve replacement (TAVR) via a transaortic approach, and to our knowledge is the first case of TAVR in a patient with circumflex aortic arch.
Merrina Lan   +3 more
doaj   +1 more source

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