Results 61 to 70 of about 1,815,137 (272)

High-intensity interval exercise training before abdominal aortic aneurysm repair (HIT-AAA): protocol for a randomised controlled feasibility trial [PDF]

, 2014
Introduction: In patients with large abdominal aortic aneurysm (AAA), open surgical or endovascular aneurysm repair procedures are often used to minimise the risk of aneurysm-related rupture and death; however, aneurysm repair itself carries a high risk.
Kerr, K., Kerr, Karen, Weston, Matthew; id_orcid, Tew, G.A., Tew, Garry A, Tew, Garry, Danjoux, Gerard, Batterham, A.M., Batterham, Alan M, Alan M Batterham, Gray, Joanne, Martin, D., Danjoux, Gerard R., Nawaz, Shah, Matthew Weston, Yates, David, Weston, M., Elke Kothmann, Tew, G. A. (Garry), Gerard Danjoux, Gray, J., Weston, Matthew, Yates, D., Garry A Tew, Kothmann, Elke, Martin, Denis, Denis Martin, Martin, Denis; id_orcid, Nawaz, S., Batterham, Alan, Shah Nawaz, Kothmann, E., Joanne Gray, Danjoux, G., David Yates, Karen Kerr   +35 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Surgical Repair of Aortic Atresia in an Adult

Annals of Thoracic Surgery Short Reports
Aortic atresia is a rare congenital vascular anomaly that occurs in adults. Differentiating it from interrupted aortic arch without open surgery is difficult.
Misato Tokioka, MD, Osamu Ishida, MD, PhD, Koji Tsutsumi, MD, PhD   +2 more
doaj   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Endovascular repair of a leaking aortic-arch pseudoaneurysm using graft stent combined with chimney protection to left common carotid artery: Case report and review of literature

Journal of the Saudi Heart Association, 2018
Aortic pseudoaneurysm (PsA) is a rare but serious condition that has high mortality and morbidity rates if untreated. We report a rare case of leaking aortic-arch PsA repaired by thoracic endovascular aortic repair using graft stent with the chimney ...
Raneem Fallatah, Abdelfatah A. Elasfar, Shadha Alzubaidi, Mazen Alraddadi, Reda Abuelatta   +4 more
doaj   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Aortic arch de-branching for suspected expanding perigraft haematoma after previous acute type-A dissection repair with AMDS stent: a technique for a potential future problem

Journal of Cardiothoracic Surgery
Background Acute Stanford type- A aortic dissections make up a large part of emergency cardiac surgery. They also carry a significant burden of morbidity.
Rickesh Karsan, Niamh Shearer, Ciara Doyle, Rachel Roberts, Alsir Ahmed   +4 more
doaj   +1 more source

A case involving a bovine aortic arch contributing to blunt thoracic aortic injury of triple rupture close to the pericardial reflection

Trauma Case Reports
A blunt thoracic aortic injury is a fatal condition that often requires emergency surgery. Although injuries to the aortic isthmus are common in trauma patients, the proximal aortic arch often remains intact.
Takuma Aoki, Hidetoshi Oka, Naohiko Oki, Hirofumi Kasahara   +3 more
doaj   +1 more source

Reconstruction of the Aortic Arc through Left Thoracotomy in Patients with Isolated Coarctation and Aortic Arch Hypoplasia

Український журнал серцево-судинної хірургії, 2021
Background. The choice of surgical approach for the reconstruction of aortic arch hypoplasia is a rather controversial issue. Traditionally, left lateral thoracotomy is used to correct aortic coarctation with hypoplasia of one or more arc seg-ments ...
Y. Truba, I. Dziuryi, O. Motrechko, O. Golovenko   +3 more
doaj   +1 more source

Double Aortic Arch Surgery

Indian Journal of Vascular and Endovascular Surgery, 2015
A 4-year-old male child was admitted with a history of difficulty in swallowing, failure to thrive and recurrent respiratory tract infections. On investigations, cardiac computed tomography was suggestive of a double aortic arch (DAA) and a virtual bronchoscopy was suggestive of tracheomalacia.
SurajWasudeo Nagre, DwarkanathV Kulkarni
openaire   +1 more source