Anatomy of the ventricular septal defect in congenital heart defects: a random association?
Background A ventricular septal defect (VSD) is an integral part of most congenital heart defects (CHD). To determine the prevalence of VSD in various types of CHD and the distribution of their anatomic types.
Meriem Mostefa-Kara+2 more
doaj +1 more source
Predictive Numerical Simulations of Double Branch Stent-Graft Deployment in an Aortic Arch Aneurysm [PDF]
Total endovascular repair of the aortic arch represents a promising option for patients ineligible to open surgery. Custom-made design of stent-grafts (SG), such as the Terumo Aortic RelayBranch device (DB), requires complex preoperative measures.
arxiv
Severe aortic and arterial aneurysms associated with a TGFBR2 mutation. [PDF]
BACKGROUND: A 24-year-old man presented with previously diagnosed Marfan\u27s syndrome. Since the age of 9 years, he had undergone eight cardiovascular procedures to treat rapidly progressive aneurysms, dissection and tortuous vascular disease involving ...
A De Paepe+21 more
core +1 more source
Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma
ABSTRACT Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma (ChARM) through the integration of evidence‐based research and multicenter clinical expertise, addresses ...
Qing Ji+112 more
wiley +1 more source
Case Report: Role of numerical simulations in the management of acute aortic syndromes
Penetrating aortic ulcer (PAU) represents a subset of acute aortic syndromes characterized by high rupture risk and management challenges, particularly in elderly patients with significant comorbidities.
Antonio Rizza+7 more
doaj +1 more source
Shared molecular programs govern the formation of heart and head during mammalian embryogenesis. Development of both structures is disrupted in human chromosomal microdeletion of 22q11.2 (del22q11), which causes DiGeorge syndrome (DGS) and velo-cardio ...
Chaoshe Guo+8 more
semanticscholar +1 more source
ABSTRACT Objective To delineate the mechanism behind insurance‐related disparities in the prenatal diagnosis of a congenital heart defect (CHD). Methods This was a retrospective analysis of electronic health records of pregnant individuals whose infants received CHD surgery between 2019 and 2020 in the third‐largest United States metropolitan area. The
Joyce L. Woo+8 more
wiley +1 more source
Computer Simulations of Pulsatile Human Blood Flow Through 3D-Models of the Human Aortic Arch, Vessels of Simple Geometry and a Bifurcated Artery: Investigation of Blood Viscosity and Turbulent Effects [PDF]
We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular. A realistic pulsatile flow is used in all simulations. Calculations for bifurcation type vessels are also carried
arxiv
Cardiovascular defects in a mouse model of HOXA1 syndrome.
Congenital heart disease is one of the most common human birth defects, yet many genes and pathways regulating heart development remain unknown. A recent study in humans revealed that mutations in a single Hox gene, HOXA1 (Athabascan Brainstem Dysgenesis
Nadja Makki, M. Capecchi
semanticscholar +1 more source
Ezetimibe therapy: mechanism of action and clinical update. [PDF]
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D+2 more
core +1 more source