Results 91 to 100 of about 9,301 (196)
Neurocardiology: Brain–Heart Interactions in the Heart
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang +3 more
wiley +1 more source
Abstract Introduction Pregnant people with congenital heart disease (CHD) are a growing patient population in obstetrics, yet evidence on the risk for severe maternal morbidity (SMM) has largely been limited to studies that lack specificity for CHD. We conducted this study to demonstrate the utility of distributed data networks for obstetric research ...
Elizabeth B. Sherwin +11 more
wiley +1 more source
Abstract Introduction Cleft lip and palate (CLP) are common congenital disruptions of the orofacial cleft and are associated with numerous genetic conditions. This study examines prenatal findings, clinical outcomes, and genetic findings among prenatally diagnosed CLP, with a focus on the yield of next‐generation sequencing (NGS).
Thomas P. Kishkovich +11 more
wiley +1 more source
Placental pathology in fetuses with and without congenital heart defects
Abstract Introduction Placental histopathologic evaluation of pregnancies affected by congenital heart defects (CHDs) can provide insight into the mechanism connecting placental and fetal vascular systems. The objective of this study was to evaluate the prevalence of maternal vascular malperfusion (MVM) and fetal vascular malperfusion (FVM) lesions of ...
Tucker E. Doiron +6 more
wiley +1 more source
Non‐Invasive Assessment of Endothelial Dysfunction and Arterial Stiffness in Fontan Circulation
The Fontan procedure is the definitive treatment for complex congenital heart disease, creating a circulation without a subpulmonary ventricle. This altered hemodynamic state negatively affects endothelial function, contributing to progressive organ dysfunction and long‐term morbidity.
Amalia Baroutidou +5 more
wiley +1 more source
Predictive Value of D‐Dimer to Albumin Ratio for Outcome in Acute Type A Aortic Dissection Patients
ABSTRACT Preoperative risk assessment and identification of potential biomarkers may optimize prognostic outcomes in patients with aortic dissection patients. The relationship between the D‐dimer to albumin ratio (DAR), an emerging biomarker that has recently attracted increasing attention, and postoperative outcomes in patients with acute type A ...
Aijie Lin +4 more
wiley +1 more source
We review the characteristic changes to the limb soft tissue and neurovascular abnormalities that have been described in the congenital limb birth defect, Radial Dysplasia. These include consistent changes in muscle anatomy or absence of specific muscles, persistent median arteries and absent radial arteries and consistent alterations in neural ...
Marco Correia Duarte +6 more
wiley +1 more source
We report an autopsy case of VEXAS syndrome presenting with aggressive clinical course. Pathologically, the disease manifested as systemic granulocytic vasculitis affecting both arteries and veins, characterized by the presence of histiocytoid myeloid cells associated with low‐risk MDS.
Kayo Ueda +5 more
wiley +1 more source
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady +11 more
wiley +1 more source

