TcMAC21 mouse model recapitulates abnormal vascular physiology observed in humans with Down syndrome
Physiological Reports, Volume 13, Issue 11, June 2025.Abstract People with Down syndrome (DS) have abnormal vascular physiology, demonstrated by low systolic blood pressure (BP) and low aortic stiffness that are accompanied by endothelial dysfunction. The TcMAC21 mouse model of DS has many features observed in people with DS, although vascular physiology has not been studied.
Xiangyu Zheng +4 more
wiley +1 more source
Adiponectin and gastric fundus: A potential target for gut–brain axis dysfunctions
Physiological Reports, Volume 13, Issue 11, June 2025.Abstract Adiponectin (ADPN) is a pleiotropic hormone produced by adipose tissue involved in the control of body weight, energy expenditure, and feeding behaviors. Alongside a central effect, ADPN acts on peripheral organs such as the stomach, where it can favor gastric fundus relaxation, reinforcing central satiety signals.
R. Garella +7 more
wiley +1 more source
Frailty Assessment in Aortic Stenosis based on Dynamic Interconnection between Cardiac and Motor Systems [PDF]
arXivBackground: Aortic stenosis (AS) is the most common acquired valvar disease and is associated with increased risk for frailty. Frailty as a geriatric syndrome is associated with muscle weakness and a compromised autonomic nervous system (ANS) performance in older adults.
arxiv
A comparison of clinical paediatric murmur assessment with echocardiography [PDF]
, 2004 Objective: To compare the clinical acumen of paediatric cardiovascular examination between various hospital paediatrician grades. Design: Prospective data collection of clinical and echocardiography findings on paediatric echocardiography referrals ...
Bailey, Mark +4 more
core
Hierarchical LoG Bayesian Neural Network for Enhanced Aorta Segmentation [PDF]
arXivAccurate segmentation of the aorta and its associated arch branches is crucial for diagnosing aortic diseases. While deep learning techniques have significantly improved aorta segmentation, they remain challenging due to the intricate multiscale structure and the complexity of the surrounding tissues.
arxiv
Aortic Arch Syndrome Associated with Hypertension Due to Unilateral Renal Lesion
, 1962 Toshiaki Takasu +3 more
openalex +2 more sources
Two-Stage Elephant Trunk approach for open management of distal aortic arch and descending aortic pathology in patients with Marfan syndrome [PDF]
, 2017 Camilo A. Velásquez +7 more
openalex +1 more source
Saccular Aortic Arch Aneurysm in the Cardiovocal Syndrome
, 2021 Manh T. Tran +3 more
openalex +1 more source
A Deep Learning System for Rapid and Accurate Warning of Acute Aortic Syndrome on Non-contrast CT in China [PDF]
arXivThe accurate and timely diagnosis of acute aortic syndromes (AAS) in patients presenting with acute chest pain remains a clinical challenge. Aortic CT angiography (CTA) is the imaging protocol of choice in patients with suspected AAS. However, due to economic and workflow constraints in China, the majority of suspected patients initially undergo non ...
arxiv