Results 111 to 120 of about 432,168 (371)

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

The role of aortic compliance in determination of coarctation severity: Lumped parameter modeling, in vitro study and clinical evaluation [PDF]

, 2015
Early detection and accurate estimation of the extent of coarctation of the aorta (COA) is critical to long-term outcome. Peak-to-peak trans-coarctation pressure gradient (PKdP) higher than 20 mmHg is an indication for interventional/surgical repair ...
Dahdah, Nagib, Edelman, Elazer R, Garcia, Julio, Kadem, Lyes, Keshavarz Motamed, Zahra, Motamed, Payam K.   +5 more
core   +1 more source

King Aorta: Narrative anatomy education

Anatomical Sciences Education, Volume 18, Issue 3, Page 264-276, March 2025.
Abstract The aim of this study was to investigate the effects of narrative anatomy education and traditional anatomy education on academic achievement. The study included 64 students who were randomly divided into two groups. The two groups were (n = 32) control (Group 1) and (n = 32) experimental (Group 2). The pretest scores of the two groups were 36.
Halil Yilmaz
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Hypoplasia of the aortic arch

Патология кровообращения и кардиохирургия, 2015
An aggressive surgical approach to early repair of aortic coarctation and concomitant arch hypoplasia results in considerable improvement of the long-term outcomes of surgical treatment by reducing the number of aortic re-coarctation and arterial ...
Ю. С. Синельников, А. В. Горбатых, С. М. Иванцов, Д. С. Прохорова, М. С. Кшановская   +4 more
doaj   +1 more source

Impaired Poststenotic Aortic Pulsatility After Hemodynamically Ideal Coarctation Repair in Children [PDF]

, 2018
Using echocardiographic quantification of aortic pulsatility distal to the site of the surgical anastomosis, we evaluated whether the preoperatively impaired poststenotic aortic pulsatility returned to normal after repair of coarctation with a ...
Berdat, P., Carrel, T., Pfammatter, J.
core  

Hypoalbuminaemia predicts outcome in adult patients with congenital heart disease [PDF]

, 2015
Background In patients with acquired heart failure, hypoalbuminaemia is associated with increased risk of death. The prevalence of hypoproteinaemia and hypoalbuminaemia and their relation to outcome in adult patients with congenital heart disease (ACHD ...
Alonso-Gonzalez, R, Diller, G-P, Dimopoulos, K, Donovan, J, Gatzoulis, MA, Hooper, J, Kempny, A, Li, W, Rafiq, I, Swan, L, Uebing, A, Wort, SJ   +11 more
core   +1 more source

Endothelium‐Independent Relaxation of Alkaloid Boldine in Isolated Aortas From Normotensive and Hypertensive Rats: Participation of Ca2+ Channels

Chemistry &Biodiversity, EarlyView.
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo, Rita de Cássia Vilhena da Silva, Valdir Cechinel Filho, Priscila de Souza   +3 more
wiley   +1 more source

Single-stage repair of adult aortic coarctation and concomitant cardiovascular pathologies: a new alternative surgical approach

Journal of Cardiothoracic Surgery, 2006
Background Coarctation of the aorta in the adulthood is sometimes associated with additional cardiovascular pathologies that require intervention. Ideal approach in such patients is uncertain.
Saba Davit, Polat Bulent, Yilmaz Mert
doaj   +1 more source

Perventricular Device Closure of Native Congenital Muscular Ventricular Septal Defects in Small Infants   $\hspace{0.17em}$ ≤ 5 kg: Single‐Center Study of the Risk Factors for Failure of the Intervention and Non‐Optimal Outcome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Perventricular device closure of muscular VSD in small infants is a less invasive option than surgical closure under cardiopulmonary bypass and offers better outcomes than palliative pulmonary artery banding. However, the specific risk factors that could affect procedural success and optimal outcomes have not been ...
Emine Hekim Yilmaz, Ilker Kemal Yucel, Murat Surucu, Huseyin Karadag, Ibrahim Halil Demir, Murat Cicek, Numan Ali Aydemir, Ahmet Celebi   +7 more
wiley   +1 more source