Results 231 to 240 of about 17,668 (270)
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang+7 more
wiley +1 more source
Surgical technical experience of adult aortic coarctation concomitant with poststenotic aneurysm or dissection. [PDF]
Qiao H, Yang B, Rotzinger DC, Liu Y.
europepmc +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler+4 more
wiley +1 more source
Comparison of Sternotomy Access Versus Thoracotomy Access in the Surgical Treatment of Aortic Coarctation: A Propensity Score-matched Study. [PDF]
Soynov IA+10 more
europepmc +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli+17 more
wiley +1 more source
The Management of Aortic Coarctation Associated with Hypoplastic Arches and Particular Arch Anatomies: A Literature Review. [PDF]
Margarint IM+9 more
europepmc +1 more source
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely+14 more
wiley +1 more source
Comparative Analysis of Surgical and Endovascular Approaches for Isolated Aortic Coarctation Repair across Age Groups: Outcomes and Long-Term Efficacy. [PDF]
Dikmen N+6 more
europepmc +1 more source
ABSTRACT Background and Aims Percutaneous pulmonary valve implantation was introduced two decades ago as a low‐risk alternative for patients previously operated with conduits presenting RVOT dysfunction. Recently, Sapien valve was approved for use in the pulmonary position but this valve cannot be used for RVOT larger than 29 mm.
João Luiz Langer Manica+13 more
wiley +1 more source