Results 41 to 50 of about 26,000 (247)

Incidental finding of undiagnosed aortic coarctation in an elderly patient with a rare association with thymic carcinoma: a case report with review of the literature

Radiology Case Reports, 2023
Aortic coarctation is a congenital malformation that is relatively prevalent, occurring in approximately 5 out of every 1000 births. The narrowing typically happens at the aortic isthmus between the left subclavian artery and the arterial ligament. It is
Manar Ezzahi, MD, Ayman Bijbij, MD, Amal Akammar, MD, Nizar El Bouardi, MD, Meriem Haloua, MD, Moulay Youssef Alaoui Lamrani, MD, Meryem Boubbou, MD, Mustapha Maaroufi, MD, Badreeddine Alami, MD   +8 more
doaj   +1 more source

Aortic stenting in the growing sheep causes aortic endothelial dysfunction but not hypertension: Clinical implications for coarctation repair [PDF]

, 2016
Stent implantation is the treatment of choice for adolescents and adults with aortic coarctation (CoAo). Despite excellent short-term results, 20%-40% of the patients develop arterial hypertension later in life, which was attributed to inappropriate ...
Aresu, Luca, Basso, Cristina, Bernardini, Daniele, Cattelan, Arianna, Ceolotto, Giulio, DE BENEDICTIS, GIULIA MARIA, Gerardi, Gabriele, Iacopetti, Ilaria, Maschietto, Nicola, Milanesi, Ornella, Pilla, Tommaso, Poser, Helen, Rizzo, Stefania, Semplicini, Andrea, Semplicini, Luca   +14 more
core   +2 more sources

Management of Severe Coarctation of the Aorta and Bilateral Carotid Artery Stenosis

JACC: Case Reports, 2023
We present a case of an adult with concurrent severe aortic coarctation, bilateral carotid artery stenosis, and anomalous right subclavian artery, posing the interventional dilemma of accepting potential cerebral hyperperfusion syndrome vs hypoperfusion ...
Alice N.W. Leung, MBBS, Karan Rao, MD, BMed, MPH, Jun Kim, BSc (Med), MBBS, Brendan Steinfort, MBBS, Nikhil Vasan, BSc, MD, David Tanous, MBBS, PhD, Chi-Jen Hsu, MBBS, BSc (Hons 1), MMed, PhD   +6 more
doaj   +1 more source

Endovascular management of a rare complication of an aortic coarctation

Radiology Case Reports, 2018
A 28-year-old pregnant woman presents with arterial hypertension of the upper limbs. The examination suggests an aortic coarctation. After a normal delivery, a contrast-enhanced computed tomography revealed a subocclusive aortic coarctation of the ...
Ahoury N'guessan Judicael, MD, Michael Vouche, MD, David Denaeghel, MD, Salvatore Murgo, MD, José Ferreira, PhD   +4 more
doaj   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Computational simulations demonstrate altered wall shear stress in aortic coarctation patients previously treated by resection with end-to-end anastomosis [PDF]

, 2011
Background.  Atherosclerotic plaque in the descending thoracic aorta (dAo) is related to altered wall shear stress (WSS) for normal patients. Resection with end-to-end anastomosis (RWEA) is the gold standard for coarctation of the aorta (CoA) repair, but
Cava, Joseph Richard, Chan, Frandics P, Dholakia, Ronak Jashwant, Feinstein, Jeffrey A., Figueroa, Alberto, LaDisa, John F., Samyn, Margaret M, Taylor, Charles A., Vignon-Clementel, Irene E   +8 more
core   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Internal mammary artery dilatation in a patient with aortic coarctation, aortic stenosis, and coronary disease. Case report

Journal of Cardiothoracic Surgery, 2011
The ideal surgical approach is unclear in adult patients with coarctation of the aorta that is associated with other cardiovascular pathologies that require intervention. Standard median sternotomy allows simultaneous, coronary revascularization surgery,
Martinez Cereijo Jose M, Martinez-de-Alegria Anxo, Martinez Comendador Jose M, Quiroga Juan, Lopez Laura, Alvarez Jose, Dominguez Cristian   +6 more
doaj   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Ascending to descending aortic prosthesis with reimplantation of brachiocephalic vessels in aneurysm of the arch and descending aorta for hypoplasia of the arch and coarctation of the aorta [PDF]

Кардіохірургія та інтервенційна кардіологія, 2020
Thoracic aortic aneurysm is one of the most serious pathologies of cardiovascular surgery. Occurrence of an aneurysm in the proximal or distal part of the aortic arch is a recognized complication of uncorrected aortic coarctation and is associated with a
B.M. Todurov, O.V. Zelenchuk, S.M. Sudakevych, A.Yu. Shkandala, N.S. Gnoyanko   +4 more
doaj   +1 more source