Presence Of A Congenitally Bicuspid Aortic Valve Among Patients Having Combined Mitral And Aortic Valve Replacement [PDF]
, 2012 Although bicuspid aortic valve occurs in an estimated 1% of adults and mitral valve prolapse in an estimated 5% of adults, occurrence of the 2 in the same patient is infrequent.
Hamman, Baron Lloyd +5 more
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Advanced Science, EarlyView.In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou +17 more
wiley +1 more source
Journal of Cardiothoracic Surgery, 2011 The ideal surgical approach is unclear in adult patients with coarctation of the aorta that is associated with other cardiovascular pathologies that require intervention. Standard median sternotomy allows simultaneous, coronary revascularization surgery,
Martinez Cereijo Jose M +6 more
doaj +1 more source
Ascending to descending aortic prosthesis with reimplantation of brachiocephalic vessels in aneurysm of the arch and descending aorta for hypoplasia of the arch and coarctation of the aorta [PDF]
Кардіохірургія та інтервенційна кардіологія, 2020 Thoracic aortic aneurysm is one of the most serious pathologies of cardiovascular surgery. Occurrence of an aneurysm in the proximal or distal part of the aortic arch is a recognized complication of uncorrected aortic coarctation and is associated with a
B.M. Todurov +4 more
doaj +1 more source
Spontaneous subarachnoid haemorrhage due to coarctation of aorta and intraspinal collaterals : a rare presentation [PDF]
, 2012 The occurrence of spontaneous subarachnoid haemorrhage (SAH) in association with coarctation of thoracic aorta and absence of intracranial aneurysm is a rare association.
Devara, Anil K.V. +2 more
core
Advanced Science, EarlyView.The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee +28 more
wiley +1 more source
Computational simulations demonstrate altered wall shear stress in aortic coarctation patients previously treated by resection with end-to-end anastomosis [PDF]
, 2011 Background. Atherosclerotic plaque in the descending thoracic aorta (dAo) is related to altered wall shear stress (WSS) for normal patients. Resection with end-to-end anastomosis (RWEA) is the gold standard for coarctation of the aorta (CoA) repair, but
Cava, Joseph Richard +8 more
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Age- and Lesion-Related Comorbidity Burden Among US Adults With Congenital Heart Disease: A Population-Based Study. [PDF]
, 2019 Background As patients with congenital heart disease (CHD) are living longer, understanding the comorbidities they develop as they age is increasingly important.
Agarwal, Anushree +9 more
core +1 more source
Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease
Advanced Science, EarlyView.Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley +1 more source
The role of posterior aortopexy in the treatment of left mainstem bronchus compression [PDF]
, 2016 OBJECTIVES: We reviewed the role of posterior aortopexy for left mainstem bronchus compression in infants and children. METHODS: Eighteen children with respiratory symptoms were enrolled between 2005 and 2015 for surgical decompression of the left ...
Arcieri, Luigi +9 more
core +1 more source