Results 61 to 70 of about 431,591 (352)

Treating a 20 mm Hg Gradient Alleviates Myocardial Hypertrophy in Experimental Aortic Coarctation [PDF]

, 2017
Background Children with coarctation of the aorta (CoA) can have a hyperdynamic and remodeled left ventricle (LV) from increased afterload. Literature from an experimental model suggests the putative 20 mm Hg blood pressure gradient (BPG) treatment ...
Friehs, Ingeborg, Harmann, Leanne, LaDisa, John F., Samyn, Margaret M., Wendell, David C.   +4 more
core   +1 more source

The role of posterior aortopexy in the treatment of left mainstem bronchus compression [PDF]

, 2016
OBJECTIVES: We reviewed the role of posterior aortopexy for left mainstem bronchus compression in infants and children. METHODS: Eighteen children with respiratory symptoms were enrolled between 2005 and 2015 for surgical decompression of the left ...
Arcieri, Luigi, Assanta, Nadia, Baggi, Roberto, DI MAURIZIO, Marco, Mirabile, Lorenzo, Moschetti, Riccardo, Murzi, Bruno, Nenna, Raffaella, Noccioli, Bruno, Serio, Paola   +9 more
core   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

In Silico Modelling of Aortic Strain and Strain Rate in Aortic Coarctation Treated with Stent Angioplasty with Comparison to Clinical Cohorts

Applications in Engineering Science, 2022
: Objective: Treatment of aortic coarctation has seen a shift from traditional surgical repair to the use of aortic stents. The aim of this study was to assess the impact upon hemodynamics and arterial strain when aortic coarctation is treated with a ...
Nicholas Gaddum, Des Dillon-Murphy, Richard Arm, Isma Rafiq, Radomir Chabiniok, Gareth Morgan, Tobias Schaeffter, Tarique Hussain   +7 more
doaj  

Iatrogenic Aortic Coarctation [PDF]

Circulation, 2007
A 35-year-old male was admitted because of arterial hypertension in the upper part of the body (230/100 mm Hg on the right arm) with a pressure difference of 50 mm Hg between the right and left arms and 80 mm Hg between the right arm and right leg. Three weeks earlier, he had undergone emergency aortic stenting for traumatic dissection at the aortic ...
Grzegorz Styczynski, Ryszard Pacho, Eugeniusz Szpakowski, Piotr Pruszczyk, Andrzej Biederman, Malgorzata Szostek   +5 more
openaire   +1 more source

Impact of complex congenital heart disease on the prevalence of arterial hypertension after aortic coarctation repair

European Journal of Cardio-Thoracic Surgery, 2018
OBJECTIVES This study was designed to evaluate the difference in the prevalence of long-term arterial hypertension among patients with corrected aortic coarctation according to the existence of associated cardiac congenital lesions.
U. Giordano, M. Chinali, A. Franceschini, G. Cafiero, M. Yammine, G. Brancaccio, S. Giannico   +6 more
semanticscholar   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

Management strategies in aortic coarctation [PDF]

European Journal of Cardio-Thoracic Surgery, 2011
Fruh et al .( 1) report their data from a retrospective study of coarctations. The small number of patients in each group and the lopsided distribution of patients in each arm render statistical analysis meaningless. The data in the abstract are different from that in the text. (Abstract: Group A, B and C: n= 48/16/27. Results section: Group A, B and C:
Ganesh Shanmugam, Gyaandeo Maharajh
openaire   +3 more sources

Computational simulations demonstrate altered wall shear stress in aortic coarctation patients previously treated by resection with end-to-end anastomosis [PDF]

, 2011
Background.  Atherosclerotic plaque in the descending thoracic aorta (dAo) is related to altered wall shear stress (WSS) for normal patients. Resection with end-to-end anastomosis (RWEA) is the gold standard for coarctation of the aorta (CoA) repair, but
Cava, Joseph Richard, Chan, Frandics P, Dholakia, Ronak Jashwant, Feinstein, Jeffrey A., Figueroa, Alberto, LaDisa, John F., Samyn, Margaret M, Taylor, Charles A., Vignon-Clementel, Irene E   +8 more
core   +1 more source