Results 71 to 80 of about 26,000 (247)

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

An unusual aortic coarctation [PDF]

Thorax, 1968
An unusual variety of aortic coarctation is described in which the left common carotid, left subclavian, and aberrant right subclavian arteries arose distal to the coarcted segment. The literature relating to unusual coarctation is briefly reviewed.
B T, Le Rous, M A, Williams
openaire   +2 more sources

Ethnical variations in the incidence of congenital heart defects in Gorgan, Northern Iran: A single-center study [PDF]

, 2014
Background: Congenital heart disease (CHD) is the most common congenital anomaly in newborns. This study was performed to determine the live birth incidence of CHD by ethnicity and sex in Gorgan, Northern Iran.
Golalipour, M.J., Nikyar, A., Nikyar, B., Qorbani, M., Sedehi, M.   +4 more
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

The value of chest x-ray in the diagnosis of aortic coarctation

Евразийский Кардиологический Журнал
Aortic coarctation is a form of generalized arteriopathy and is not limited to narrowing of the aorta. It can develop as a local stenosis, or as an extended one, in the form of hypoplasia of the aortic segment [1].The symptoms and signs depend on the ...
I. Z. Korobkova, N. V. Buldakova, A. Yu. Matchina, O. V. Stukalova, S. A. Gaman   +4 more
doaj   +1 more source

Corkscrew aortic arch in PHACES syndrome: Multimodal imaging of an unusual morphology of tortuous aortic arch in a rare but well-defined syndrome

Annals of Pediatric Cardiology, 2019
PHACES syndrome, a diffuse aortocraniocerebral vasculopathy, is a neural tube migration disorder, characterized by aortic coarctation and aberrant arch branches.
Ronak Sheth, Arvind Sahay Singh, Sreeja Pavithran, Kothandam Sivakumar   +3 more
doaj   +1 more source

A prospective observational multicenter study of balloon angioplasty for the treatment of native and recurrent coarctation of the aorta [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106945/1/ccd25284 ...
Bald, Brown, Campbell, Cowley, Fawzy, Fawzy, Fixler, Forbes, Fruh, Gillett, Hernandez-Gonzalez, Hijazi, Hornung, Instebo, Jimenez, McGuinness, Pedersen, Porras, Rodes-Cabau, Tanous, Vogt, Vriend, Walhout, Walhout, Yetman   +24 more
core   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Single stage repair for aortic root aneurysm in a patient with coexisting coarctation incorporating the Cabrol technique: a case report

Journal of Cardiothoracic Surgery, 2018
Background A 44 year old man who presented with a history of chest pain and dyspnoea was found to have an aneurysm of the aortic root, aortic valve insufficiency, and coarctation of the aorta.
Yassir Iqbal, Omar A. Jarral, Pantelis Tsipas, Ilias Samiotis, Theodoros Kratimenos, John Kokotsakis, Thanos Athanasiou   +6 more
doaj   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source