Results 251 to 260 of about 886,119 (323)

NONO‐Related Syndromic X‐Linked Developmental Disability 34: Further Clinical and Molecular Delineation in a Prenatal Cohort

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To characterize the prenatal sonographic features across different trimesters and genomic spectrum of NONO‐related X‐linked intellectual developmental disorder. Method We analyzed two fetuses presenting with corpus callosum agenesis and rare cardiac anomalies using genome sequencing and exome sequencing.
Yilin Zhao, Gang Zou, Mengmeng Shi, Kwok Ming Law, So Ling Lau, Meng Meng, Yuen Ha Ting, Chiu Yee Liona Poon, Zirui Dong, Matthew Hoi Kin Chau, Tak Yeung Leung, Kwong Wai Choy, Xinwen Zhang, Ye Cao   +13 more
wiley   +1 more source

Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement: A meta‐analysis

Precision Medical Sciences, EarlyView.
Central illustration: Sex‐based differences in outcomes between male and female patients with bicuspid aortic stenosis following transcatheter aortic valve replacement. Abstract Bicuspid aortic valve (BAV) is a common congenital anomaly leading to early aortic stenosis.
Muhammad Huzaifa Ahmed Khan, Muneeb Khawar, Asad Ullah Farooq, Azooba Khalid, Syed Muhammad Ahsan, M. Hamza Naseer Awan, Muhammad Soban Nisar, Asim Elahi, Muhammad Aqib Faizan, Iqra Shahid, Abdullah Munir Ahmed, Faseeh Haider, Rejina Chhetri   +12 more
wiley   +1 more source

A smaller heart-aorta-angle associates with ascending aortic dilatation and increases wall shear stress. [PDF]

Eur Radiol, 2020
Kauhanen SP, Liimatainen T, Kariniemi E, Korhonen M, Parkkonen J, Vienonen J, Vanninen R, Hedman M.   +7 more
europepmc   +1 more source

MRI‐based qualitative, quantitative, and radiomics/deep learning methods for assessing treatment response after neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer

Precision Radiation Oncology, EarlyView.
MRI, owing to its superior soft tissue contrast and spatial resolution, has become the preferred noninvasive modality for assessing nCRT efficacy. This review synthesizes current evidence on MRI‐based assessment of nCRT efficacy in LARC and discusses future directions.
Shuang Chen, Lin Liu, Guangwei Tian, Ruimei Chai   +3 more
wiley   +1 more source

Epicardial adipose tissue is a predictor of ascending aortic dilatation in hypertensive patients, but not paracardial adipose tissue. [PDF]

BMC Cardiovasc Disord, 2020
Argan O, Avci E, Yildirim T, Safak O.
europepmc   +1 more source

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

Released Granulocytic Elastase [PDF]

, 1985
Duswald, Karl-Heimo, Fritz, Hans, Jochum, Marianne, Schramm, Wolfgang   +3 more
core  

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, EarlyView.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

Osteoprotegerin Deficiency Limits Angiotensin II–Induced Aortic Dilatation and Rupture in the Apolipoprotein E–Knockout Mouse

Arteriosclerosis, Thrombosis and Vascular Biology, 2014
C. Moran, Roby J. Jose, E. Biros, J. Golledge   +3 more
semanticscholar   +1 more source

Aortic dilation in turner syndrome

Journal of the American College of Cardiology, 1998
Sharma, J.R., Friedman, D.M., Dave-Sharma, S.J., Harbison, M.   +3 more
openaire   +1 more source