Background: After the arterial switch operation (ASO) for transposition of the great arteries (TGA), neo-aortic dilatation and coronary arterial anomalies, especially an interarterial course and acute coronary artery take-off angle, are commonly found ...
Diederick B.H. Verheijen +12 more
doaj +1 more source
Background: Cardiovascular abnormalities have been observed in patients with mucopolysaccharidosis (MPS) of any type, with the most documented abnormalities being valvular regurgitation and stenosis and cardiac hypertrophy.
Hsiang-Yu Lin +8 more
doaj +1 more source
Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome [PDF]
Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS): the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1); and the revised Ghent nosology in 2010 (Ghent-2).
Bannas, Peter +13 more
core +2 more sources
TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc +12 more
core +2 more sources
ObjectiveTo assess aortic dilatation and determine its related factors in infants with coarctation of the aorta (CoA) by using computed tomography angiography (CTA).MethodsThe clinical data of 55 infantile patients with CoA diagnosed by CTA were analyzed
Hui-Jun Xiao +4 more
doaj +1 more source
Evolution of the wall shear stresses during the progressive enlargement of symmetric abdominal aortic aneurysms. [PDF]
The changes in the evolution of the spatial and temporal distribution of the wall shear stresses (WSS) and gradients of wall shear stresses (GWSS) at different stages of the enlargement of an abdominal aortic aneurysm (AAA) are important in understanding
Chomaz, JM +3 more
core +4 more sources
Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy
BackgroundThe mechanism underlying aortic dilatation is still unknown. Vascular dilatation is thought to be the result of progressive aortic media degeneration caused by defective vascular matrix hemostasis, including TGF-β1 dysregulation.
Mikita Karalko +6 more
doaj +1 more source
Progressive thoracic aortic dilatation after aortic valve replacement [PDF]
Aneurysms of the ascending aorta developed after aortic valve replacement for chronic aortic insufficiency in four cases. Two of the aneurysms were complicated by dissection; one patient died. Rheumatic disease has become a less common cause of pure aortic regurgitation, and a number of etiologies primarily involving the wall of the aorta are now ...
P A, Nancarrow, C B, Higgins
openaire +2 more sources
Pathological Investigation of Congenital Bicuspid Aortic Valve Stenosis, Compared with Atherosclerotic Tricuspid Aortic Valve Stenosis and Congenital Bicuspid Aortic Valve Regurgitation [PDF]
Congenital bicuspid aortic valve (CBAV) is the main cause of aortic stenosis (AS) in young adults. However, the histopathological features of AS in patients with CBAV have not been fully investigated.We examined specimens of aortic valve leaflets ...
A Mazzone +40 more
core +3 more sources
The bicuspid aortic valve - studies on valve morphology and pathology in relation to ascending aortic dilatation and coronary artery disease [PDF]
The prevalence of bicuspid aortic valve (BAV) is 1 - 2% and is thereby the most common cardiac malformation. BAV is highly associated with valvular dysfunction and aortic co nditions such as ascending aortic aneurysm and aortic ...
Jackson, Veronica
core +1 more source

