Results 211 to 220 of about 80,898 (310)
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
Aortic Dissection in a Patient With Fontan Physiology: Complex Emergency Repair and Tailored Coronary Reconstruction. [PDF]
Mourad N +7 more
europepmc +1 more source
BJU International, Volume 135, Issue 4, Page 700-705, April 2025.
Yubo Wang +10 more
wiley +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Bilateral Renal Artery Thrombosis With Distal Abdominal Aortic Dissection as the First Presentation of Takayasu Arteritis. [PDF]
Thanigasalan M +2 more
europepmc +1 more source
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Prognostic Value of a Composite Inflammation-Renal Function Score in Type A Aortic Dissection. [PDF]
Zhou RQ, Peng YD, Cai H, Zhang C, Wu QC.
europepmc +1 more source
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Iliac branch device for infrarenal aortic dissection: A novel off-label strategy. [PDF]
Ardiles D +4 more
europepmc +1 more source

