Results 41 to 50 of about 105,281 (259)

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Chronic β-blocker therapy improves outcome and reduces treatment costs in chronic type B aortic dissection [PDF]

, 2017
Objectives: To compare the medical treatment of chronic type B aortic dissection with β-blockers versus other antihypertensive treatments in terms of their requirement for surgical intervention and treatment costs.
Genoni, Michele, Graves, Kirk, Jenni, Rolf, Paul, Matthias, Seifert, Burkhardt, Turina, Marko   +5 more
core  

Acute aortic dissection in a young healthy athlete with androgenic anabolic steroid use: A case report [PDF]

, 2014
Background: Acute aortic dissection can occur at the time of intense physical exertion in strength-trained athletes like weight lifters, bodybuilders, throwers, and wrestlers.
Barman M, Djamel B, Mathews J
core   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Aortic dissection or myocardial infarction [PDF]

, 2011
Aortic dissection is a rare and a life threatening event. Classically, aortic dissection presents as sudden, severe chest, back or abdominal pain that is characterized as ripping or tearing in nature.
Ashfaq, Awais, Fatimi, Saulat H., Mahboob, Maria   +2 more
core   +2 more sources

Heart failure and sudden cardiac death in heritable thoracic aortic disease caused by pathogenic variants in the SMAD3 gene [PDF]

, 2018
Background: Predominant cardiovascular manifestations in the spectrum of Heritable Thoracic Aortic Disease include by default aortic root aneurysms- and dissections, which may be associated with aortic valve disease.
Aalberts, Alpendurada, Audenaert, Backer, Campens, Chen, Cook, Gott, Hoffmann, Kesler, Kiotsekoglou, Kiotsekoglou, Knosalla, Laar, Linde, Loeper, Murdoch, Pyeritz, Regalado, Rouf, Rybczynski, Schaeffer, Tae, Yetman   +23 more
core   +2 more sources

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

Advanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen, Yifeng Zhang, Mirenuer Aikebaier, Yawei Du, Yan Liu, Qing Zha, Lan Zheng, Shuyao Shan, Yanping Wang, Jiawei Chen, Yiping Li, Ke Yang, Ying Yang, Wenguo Cui   +13 more
wiley   +1 more source

Repair of stent graft-induced retrograde type A aortic dissection using the E-vita open prosthesis† [PDF]

, 2017
OBJECTIVES Stent graft-induced retrograde type A dissection is a life-threatening complication after endovascular treatment of acute aortic type B dissections.
Czerny, Martin, Folkmann, Sandra, Gorlitzer, Michael, Grabenwöger, Martin, Moidl, Reinhard, Waldenberger, Ferdinand, Weiss, Gabriel   +6 more
core  

Adventitial inversion technique without the aid of biologic glue or Teflon buttress for acute type A aortic dissection [PDF]

, 2005
Objective: This study was performed to evaluate the clinical usefulness of the adventitial inversion technique in acute type A aortic dissection, with special attention to the impact of this procedure on the postoperative status of false lumen evaluated ...
57277, 57278, 57279, 57280, 57281, 57282, 57283, 57284, HANDA, Mitsuteru, IHAYA, Akio, Li, Wei, MORIOKA, Kouichi, TAKAMORI, Atsushi, TANABE, Sawaka, TANAKA, Kuniyoshi, YAMADA, Narihisa   +15 more
core   +1 more source

Intraoperative aortic dissection

Annals of Cardiac Anaesthesia, 2015
Intraoperative aortic dissection is a rare but fatal complication of open heart surgery. By recognizing the population at risk and by using a gentle operative technique in such patients, the surgeon can usually avoid iatrogenic injury to the aorta.
Ajmer Singh, Yatin Mehta
openaire   +4 more sources