Results 141 to 150 of about 1,982,028 (198)

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

Aging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng, Xiaozhu Zeng, Jing Guo, Lihong Li, Shirui Zou, Nan Liu, Shuai He, Lanzhen Yan, Qiong Wang, Yongjie Zhu, Ben Wang, Dong Yang, Longbao Lv, Xudong Zhao   +13 more
wiley   +1 more source

Clamshell Thoracosternotomy for Single-Stage Repair of a Rare Aortic Graft Infection Involving Ascending, Arch, and Descending Aortic Pathologies. [PDF]

Cureus
MacKinnon MJ, Ferguson DB, White CW, Cloutier J, Légaré JF.   +4 more
europepmc   +1 more source

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study

Andrology, Volume 14, Issue 7, Page 2262-2273, October 2026.
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova, Nancy Babio, Cristina Valle‐Hita, María Fernández de la Puente, Alfonso Beltran‐Arasa, Miguel Cebrián‐Puig, Violeta Fambuena‐Perez, Iván García‐Serrano, Michelle M. Murphy, Jordi Salas‐Salvadó, Albert Salas‐Huetos   +10 more
wiley   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

Artificial Organs, Volume 50, Issue 10, Page 1464-1475, October 2026.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci, Anne‐Kristin Schaefer, Thomas Schlöglhofer, Emilio Osorio‐Jaramillo, Amila Kahrovic, Alvaro Perazzo, Marcus Granegger, Daniel Zimpfer, Dominik Wiedemann, Julia Riebandt   +9 more
wiley   +1 more source

Complex Aortic Graft Infection with Giant Collection after Bentall-Bono Surgery: Diagnostic and Therapeutic Challenges. [PDF]

JACC Case Rep
Cabrera FS, Sabate PR, Valente FX, Fernandez-Hidalgo N, Camazón NV, Roque A, Teixidó-Taura G, Rodriguez-Palomares JF.   +7 more
europepmc   +1 more source

Early Multicenter Outcomes of Dedicated Transcatheter Aortic Valve Replacement for Left Ventricular Assist Device‐Associated Pure Aortic Regurgitation

Artificial Organs, Volume 50, Issue 10, Page 1427-1433, October 2026.
LVAD‐associated aortic regurgitation impairs circulatory support, with limited surgical and off‐label options. In a multicenter registry (n = 30), the AR‐dedicated JenaValve Trilogy TAVR eliminated AR, achieving 96.7% (29/30) technical success and 93.3% (28/30) device success (VARC‐3), with 3.3% (1/30) 30‐day mortality.
Hristian Hinkov, Sara Yousefzada, Isabell A. Just, Christoph Klein, Evgenij Potapov, Santiago Garcia, Dhairya Patel, Lauren S. Ranard, Arseniy Goncharov, Dean J. Kereiakes, Raj R. Makkar, Torsten P. Vahl, Tanja K. Rudolph, Axel Unbehaun   +13 more
wiley   +1 more source

Evasins: Biology and Therapeutic Potential of Broad‐Spectrum Chemokine Inhibitors

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Emilia L. Bialek, Roos Buds, Ingrid Dijkgraaf, Pedro E. Marques   +3 more
wiley   +1 more source

Mycobacterium bovis: An unusual cause of aortic graft infection. [PDF]

Radiol Case Rep
Colantonio MA, Pokharel S, Dionne C, Leibrock S.   +3 more
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source