Results 251 to 260 of about 92,271 (323)

Trial‐Based Hemolysis Modeling to Investigate Operating Modes of Continuous‐Flow LVADs

Artificial Organs, EarlyView.
This work presents a methodology for determining online‐capable hemolysis models for continuous‐flow LVADs, derived from in vitro trials. The models are based on fitting a modified power law and applying the Lagrangian approach. They assist clinicians in selecting treatment strategies that minimize hemolysis, as demonstrated with the Sputnik1 LVAD ...
Patrick Borchers, Steffen Leonhardt, Marian Walter   +2 more
wiley   +1 more source

Hydraulic In Vitro Characterization of MR‐Conditional Blood Pumps

Artificial Organs, EarlyView.
Cardiac surgery in neonates requires close placement of cardiopulmonary bypass machines due to limited blood volume, complicating MR compatibility. This study introduces three MR‐conditional blood pump prototypes. None interfered with MRI imaging, though RF‐related sensor effects remain untested.
Dominik T. Schulte, Marcel Renggli, Henning Richter, Francesca Del Chicca, Michael Hofmann, Martin O. Schmiady, Marianne Schmid Daners   +6 more
wiley   +1 more source

Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support

Artificial Organs, EarlyView.
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Anton Heller, Dzmitry Turtsevich, Christian Schach, Peter‐Paul Ellmauer, Walter Petermichl, Bernhard Flörchinger, Christof Schmid, Simon Schopka, Zdenek Provaznik   +11 more
wiley   +1 more source

Percutaneous Versus Surgical Cannulation for Femoro‐Femoral Venoarterial Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study on Cannulation‐Related Complications

Artificial Organs, EarlyView.
Percutaneous femoro‐femoral V‐A ECMO cannulation was associated with more than a two‐fold lower risk of site bleeding and nearly a six‐fold lower risk of infection compared with surgical cut‐down, with no difference in limb ischemia. Absence of distal perfusion catheterization and larger arterial cannula size were additional modifiable ischemia risk ...
Axel Dimberg, Magnus Dalén, Anders Franco‐Cereceda, Thomas Fux   +3 more
wiley   +1 more source

Transcatheter Aortic Valve Implantation for Severe Aortic Insufficiency Due to Infective Endocarditis in a Patient with Cirrhosis and Hepatocellular Cancer: A Novel Indication.

Heart Views
Abujalala S, Ede H, Abdullatef WK, Al-Hijji MA.   +3 more
europepmc   +1 more source

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

British Journal of Pharmacology, EarlyView.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero, Sarah Torp Yttergren, Max Hahn, Marie Biviano Rosenkilde, Ditte Marie Jensen, Michael Christensen, Louise Thisted, Heidi Lindgreen Holmberg, Geoffrey Teixeira, Tor Biering‐Sørensen, Casper Gravesen Salinas, Urmas Roostalu   +11 more
wiley   +1 more source

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

Clinical Genetics, EarlyView.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum, Maya Slovik, Shamir Zenvirt, Ilana Livyatan, Israel Altman, Shiri Gershon, Jonathan Rips, Hagit Daum, Chaggai Rosenbluh, Orly Elpeleg, Vardiella Meiner, Ayala Frumkin, Hagar Mor‐Shaked, Tamar Harel   +13 more
wiley   +1 more source

Preoperative and Long-Term Postoperative Echocardiographic Evaluation of Chronic Aortic Insufficiency; Optimal Timing for Aortic Valve Replacement

, 1984
Dong Sun Han, Sung Wook Park, Jung Hyun Kim, Yun Sik Choi, Jungdon Seo, Young Woo Lee, Young‐Kyun Lee   +6 more
openalex   +1 more source

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

Clinical Genetics, EarlyView.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson, Daniel E. McGinn, T. Blaine Crowley, Lydia Rockart, Audrey Green, Victoria Giunta, Oanh Tran, Daniella Miller, Jeroen Breckpot, Ann Swillen, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Federica Pulvirenti, Bruno Marino, Beverly S. Emanuel, Elaine H. Zackai, Zhengdong D. Zhang, Elizabeth Goldmuntz, Erik Boot, Anne S. Bassett, Bernice E. Morrow, Donna M. McDonald‐McGinn   +22 more
wiley   +1 more source

A case of progressive right ventricular failure with ventricular arrhythmia and aortic insufficiency after implantable left ventricular assist device implantation. [PDF]

J Cardiol Cases
Jimba T, Hatano M, Fujiwara T, Akazawa H, Watanabe M, Kinugawa K, Ono M, Komuro I.   +7 more
europepmc   +1 more source