Results 271 to 280 of about 92,271 (323)

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

The Swedish CArdioPulmonary bioImage Study re‐examination: Rationale, design, methods, and management of incidental findings

Journal of Internal Medicine, EarlyView.
Abstract Objectives To describe the rationale, design and data collection procedures of the Swedish CArdioPulmonary bioImage Study (SCAPIS) re‐examination, which, in its further scope, aims to quantify and explain the development of atherosclerosis, pathological cardiovascular ageing, longitudinal decline in lung function and the malignant ...
Elin Good, Göran Bergström, Anders Blomberg, Viiu Blöndal, Gunnar Engström, Erika Fagman, Klas Gränsbo, Shabab Hasan, Shadi Jalali, Tomas Jernberg, Åse Johnsson, Ioannis Katsoularis, Jeanette Kuhl, Andrei Malinovschi, Lina Malm, Vibeke Sparring, Eva Swahn, Richard Ssegonja, Jelmer Westra, Mischa Woisetschläger, Carl Johan Östgren, Emil Hagström   +21 more
wiley   +1 more source

Preoperative higher right ventricular stroke work index increases the risk of de novo aortic insufficiency after continuous-flow left ventricular assist device implantation. [PDF]

J Artif Organs
Maeda S, Toda K, Shimamura K, Nakamoto K, Igeta M, Sakata Y, Sawa Y, Miyagawa S.   +7 more
europepmc   +1 more source

From gateway to value ladder—The curious case of online mutual aid in China

Journal of Risk and Insurance, EarlyView.
Abstract This study examines how InsurTech‐enabled information provision, specifically the disclosure of claimant information previously unavailable in conventional insurance, influences individuals' insurance uptake. We leverage Mutual Aid (MA) platforms as a natural context to examine how socially framed loss information, peer influence, and salience
Ze Chen, Runhuan Feng, Miao Guo, Tianyang Wang   +3 more
wiley   +1 more source

Donor procurement for intestinal transplantation [PDF]

, 1997
Abu-Elmagd, K, Fung, JJ, Furukawa, H, Reyes, J, Starzl, TE, Todo, S   +5 more
core  

Severe Periodontitis is Associated With Recurrent Cardiovascular Events—A 10‐Year Longitudinal Cohort Study

Journal of Periodontal Research, EarlyView.
One thousand and two patients with cardiovascular disease (CVD) were observed over 10 years. Data were collected from 792 study participants. Severe periodontitis proved to be an independent risk factor for new cardiovascular events. Tooth brushing more than once a day and performing interdental hygiene were associated with decreased risk.
Stefan Reichert, Selina Rehm, Axel Schlitt, Susanne Schulz   +3 more
wiley   +1 more source

Association Between Perioperative Sleep Disorders and Post‐Operative Delirium in Cardiac Surgeries: A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
Overview of studies included in the systematic review investigating the association between perioperative sleep disorders (PSD) and postoperative delirium (POD) in patients undergoing cardiac surgery. ABSTRACT Post‐operative delirium (POD) is an acute deterioration in cognitive function and highly prevalent after cardiac surgery (CS; up to 55 ...
Hesam Varpaei, Pallav Deka, Lorraine B. Robbins, Kousha Farhadi, Mathew Reeves, Fabrice Mowbray, Stuart F. Quan   +6 more
wiley   +1 more source

A Systematic Review on Applications of Artificial Intelligence for Obesity Prevention

Obesity Reviews, EarlyView.
ABSTRACT This systematic review examines the applications of artificial intelligence (AI) in preventing obesity, addressing a critical public health issue that affects a substantial portion of the population. With obesity rates rising alarmingly, particularly in the United States, this review synthesizes findings from 46 studies published between 2008 ...
Atefehsadat Haghighathoseini, Shuo‐yu Lin, Ge Song, Ruopeng An, Hong Xue   +4 more
wiley   +1 more source

Efficacy and Safety of the Sync‐AV II Temporary Cardiac Pacing Catheter (EASY II Trial)

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Cardiac pacing is crucial for patients with hemodynamically unstable bradyarrhythmias. For most indications, transvenous pacemakers are used to pace the right ventricle, causing atrioventricular dyssynchrony, which may lead to significant hemodynamic compromise.
Som A. Bailey, Bertrand Ebner, Christian Marin y Kall, Jeffrey J. Goldberger, Santiago Gallo, Eduardo J. de Marchena   +5 more
wiley   +1 more source