Results 41 to 50 of about 96,458 (298)

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan, Naseebullah Kakar, Ainullah Kakar, Malte Spielmann, Sajid Malik   +4 more
wiley   +1 more source

The Challenges of Aortic Valve Management After Left Ventricular Assist Device Implantation

Annals of Thoracic Surgery Short Reports
Background: Continuous retrograde flow across the aortic valve from left ventricular assist device (LVAD) therapy can result in cusp damage and progressive aortic regurgitation, potentially triggering recurrent heart and multiorgan failure.
Fotios Pitoulis, MD, PhD, Karissa Tauber, MD, Pavan Atluri, MD, Wilson Szeto, MD, Saif Anwarruddin, MD, Taisei Kobayashi, MD, Nimesh Desai, MD, Marisa Cevasco, MD, Christian Bermudez, MD, Michael Acker, MD, Matthew Williams, MD, Michael Ibrahim, MD, PhD   +11 more
doaj   +1 more source

A heart in a heart: a case report of spontaneous flail of bicuspid aortic valve

Journal of Medical Case Reports, 2021
Background Aortic regurgitation is attributed to congenital and acquired abnormalities of the aortic valve or aortic valve supporting structures. The most common cause of aortic regurgitation is atherosclerotic degeneration of the valve, especially in ...
Khadije Mohammadi, Mahsa Akrami, Marzieh Mirtajaddini   +2 more
doaj   +1 more source

A novel inhaled anesthesia technique for concurrent direct laryngoscopy in rats

Animal Models and Experimental Medicine, EarlyView.
Our novel nose cone anesthetic technique allows the use of gas anesthesia during concurrent direct laryngoscopy. Inhaled anesthesia not only has a better safety profile for rats, but also increases lab efficiency when compared to injectable anesthesia. Abstract The current anesthetic standard for laryngoscopy in rats utilizes injectable intraperitoneal
Corinne Negvesky, Amin Mirzaaghasi, Eric M. Smith, Ashley E. Kita   +3 more
wiley   +1 more source

The Heart of a Horse: 3‐D Echocardiographic Analysis of the Equine Aortic Valve [PDF]

, 2019
Aortic regurgitation (AR) can be a normal function of aging or a disease in younger horses. Symptoms range from no outward signs to decreased performance to sudden cardiac arrest.
McElhinney, Amber
core   +1 more source

Prognostic value of echocardiographic indices of left atrial morphology and function in dogs with myxomatous mitral valve disease [PDF]

, 2018
Background: The prognostic relevance of left atrial (LA) morphological and functional variables, including those derived from speckle tracking echocardiography (STE), has been little investigated in veterinary medicine.
Baron Toaldo, Marco, Cipone, Mario, Contiero, Barbara, Diana, Alessia, Guglielmini, Carlo, Pelle, Nazzareno G., Romito, Giovanni   +6 more
core   +2 more sources

Mid- and Longterm Neo-Aortic Valve Regurgitation after Jatene Surgery: Prevalence and Risk Factors

Arquivos Brasileiros de Cardiologia, 2018
Background: Jatene surgery became the surgical procedure of choice to repair transposition of the great arteries (TGA) in neonates and infants. Late complications, mainly related to the pulmonary outflow tract and coronary arteries, are well known.
Cristiane Nunes Martins, Bayard Gontijo Filho, Roberto Max Lopes, Francisco das Chagas Lima e Silva   +3 more
doaj   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation. [PDF]

, 2020
BackgroundMucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT) because it stabilizes cognitive deterioration, but is insufficient to alleviate all somatic manifestations.
A Ghosh, AR Pal, ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories., B Link, Bradley S. Miller, C Peters, C Peters, Chester B. Whitley, DA Stevenson, E Shapiro, E Yasuda, E. Oussoren, EA Braunlin, EA Braunlin, ED Kakkis, EJ Langereis, Elise Northrop, Elizabeth Braunlin, Ellen B. Fung, Ellen Fung, G Malm, I Visigalli, Jakub Tolar, JB Eisengart, JE Wraith, JJ Boelens, JR Hobbs, JS Weisstein, Julie B Eisengart, Julie B. Eisengart, KJ Bjoraker, Kyle Rudser, L Lopez, LA Clarke, LE Polgreen, LE Polgreen, LE Polgreen, Lynda E. Polgreen, M Aldenhoven, M Sifuentes, MA Saif, MD Poe, NE Taylor, NJ Rodgers, Paul J. Orchard, RL Washington, S Laraway, Simon A. Jones, SS Grewal, Troy C. Lund, Weston P. Miller, Y Xue   +51 more
core   +1 more source

A Meta‐Analysis and Simplified Nomenclature for Diagonal Coronary Artery and Ramus Intermedius Across Adult and Pediatric Hearts

Clinical Anatomy, EarlyView.
ABSTRACT Anatomical descriptions of left‐sided oblique coronary branches remain inconsistent, hindering imaging interpretation and surgical planning. To quantify the prevalence, branching patterns and morphometry of the ramus intermedius (RI) and diagonal branches, and propose a unified nomenclature.
Yuqian Dai, Sabrina Constantini, Michael J. Montalbano, Marios Loukas   +3 more
wiley   +1 more source