Results 41 to 50 of about 96,734 (313)

Clinical outcomes of aortic root replacement after previous aortic root replacement [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2013
The study objective was to examine the short- and long-term outcomes of reoperative aortic root replacement after a previous aortic root replacement.From September 1985 to February 2011, 84 consecutive patients underwent reoperative aortic root replacement. The patients' mean age was 46 ± 15 years (range, 19-80 years), and 86% were men.
Luis Garrido-Olivares   +3 more
openaire   +3 more sources

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

Surgery of the dilated aortic root and ascending aorta in pediatric patients: techniques and results [PDF]

open access: yes, 2017
Objective: Dilatation of the aortic root is a well-known cardiovascular manifestation in children and adult patients with connective tissue disease (e.g. Marfan syndrome).
Berdat, Pascal   +5 more
core  

Novel Drug‐Testing Platform for Vascular Injury‐induced Intimal Hyperplasia Using a Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam   +7 more
wiley   +1 more source

Prediction of Turbulent Shear Stresses through Dysfunctional Bileaflet Mechanical Heart Valves using Computational Fluid Dynamics

open access: yes, 2018
There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease.
Gamage, Peshala T.   +2 more
core   +1 more source

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben   +8 more
wiley   +1 more source

Remodelling of the aortic root in severe tricuspid aortic stenosis: implications for transcatheter aortic valve implantation [PDF]

open access: yes, 2018
Detailed knowledge of aortic root geometry is a prerequisite to anticipate complications of transcatheter aortic valve (TAV) implantation. We determined coronary ostial locations and aortic root dimensions in patients with aortic stenosis (AS) and ...
Alkadhi, Hatem   +10 more
core  

Aortic root replacement with Freestyle stentless valve for complex aortic root infection [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2003
AbstractJ Thorac Cardiovasc Surg 2003;125:200 ...
Hidekazu Hirai   +5 more
openaire   +3 more sources

A Patient‐Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow, and Endothelium Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces the first miniaturized, patient‐specific carotid artery model created via 3D printing using GelMA with embedded vascular cells. Combining CFD, PIV, and flow perfusion, the model replicates anatomically dependent hemodynamics and cellular responses.
Jorge A. Catano   +7 more
wiley   +1 more source

Geometric models of the aortic and pulmonary roots: suggestions for the Ross procedure [PDF]

open access: yes, 2017
Objective: To discuss geometric factors, which may influence long-term results relating to homograft competence following the Ross procedure, we describe the 3D morphology of the pulmonary and aortic roots.
Berdajs, Denis   +5 more
core  

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