Results 211 to 220 of about 58,576 (312)

Targeting CRM1 for Progeria Syndrome Therapy

open access: yesAging Cell, EarlyView.
Pharmacological inhibition of CRM1 mediated by selinexor, the first‐in‐class selective inhibitor of CRM1, mitigates the senescent phenotype of Hutchinson‐Gilford progeria syndrome (HGPS) patients‐derived primary fibroblasts. Treatment of HGPS fibroblasts with selinexor promotes the clearances of progerin via autophagy activation, restores the ...
Adriana Soto‐Ponce   +14 more
wiley   +1 more source

Unusual aortic rupture: What is cold can become catastrophic! [PDF]

open access: yesIndian J Med Res, 2020
Chandrashekhara SH, Kumar S.
europepmc   +1 more source

Aging‐Associated Liver Sinusoidal Endothelial Cells Dysfunction Aggravates the Progression of Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAging Cell, EarlyView.
Aged rats and human are more susceptible to MASLD‐related liver injury, steatosis, and fibrosis, accompanied by worsening of endothelial dysfunction. The SIRT1/p‐eNOS/NO pathway is involved in aggravated MASLD caused by aging‐related LSECs dysfunction.
Qingqing Dai   +5 more
wiley   +1 more source

Endovascular Treatment With a Balloon-Expandable Covered Stent in a Polytrauma 12-Year-Old Patient With Traumatic Abdominal Aortic Rupture. [PDF]

open access: yesCureus
Florou M   +7 more
europepmc   +1 more source

Adventitial remodeling protects against aortic rupture following late smooth muscle-specific disruption of TGFβ signaling. [PDF]

open access: yesJ Mech Behav Biomed Mater, 2021
Kawamura Y   +5 more
europepmc   +1 more source

Preventing Rupture of Abdominal Aortic Aneurysm by Earlier Elective Repair [PDF]

open access: bronze, 1994
Robert C. Allen   +5 more
openalex   +1 more source

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